肥胖相关性男性生殖器硬化性苔藓
Obesity-related male genital lichen sclerosus.
作者信息
Doiron P R, Bunker C B
机构信息
Department of Dermatology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
University College London Hospitals NHS Foundation Trust, Dermatology Department, University College Hospital London, London, UK.
出版信息
J Eur Acad Dermatol Venereol. 2017 May;31(5):876-879. doi: 10.1111/jdv.14035. Epub 2016 Nov 28.
BACKGROUND
Obesity is increasing. Male genital lichen sclerosus (MGLSc) is almost exclusively a disease of the uncircumcised. An apparent increasing challenge is MGLSc in previously circumcised obese males.
OBJECTIVES
To characterise patients with obesity-related MGLSc.
METHODS
Case chart review of patients managed in specialist clinics.
RESULTS
Nineteen patients with obesity-related MGLSc were identified. All had been previously circumcised. 16 (84%) acknowledged urinary microincontinence ('dribbling'). 14 (74%) remitted with medical treatment and 5 (26%) needed specialised surgery.
CONCLUSIONS
Male genital lichen sclerosus can complicate obesity in previously circumcised patients. Management requires dermatological and specialist urological input, and can be challenging, but effective. The phenomenon increases the evidence for the role of the occlusive influence of urine in the pathogenesis of MGLSc.
背景
肥胖现象日益普遍。男性硬化性苔藓（MGLSc）几乎仅见于未行包皮环切术的男性。一个明显日益严峻的挑战是，在既往已行包皮环切术的肥胖男性中出现MGLSc。
目的
对肥胖相关MGLSc患者进行特征描述。
方法
对专科门诊治疗的患者进行病历回顾。
结果
共识别出19例肥胖相关MGLSc患者。所有患者既往均已行包皮环切术。16例（84%）承认存在尿微失禁（“滴沥”）。14例（74%）经药物治疗后病情缓解，5例（26%）需要接受专科手术。
结论
男性硬化性苔藓可使既往已行包皮环切术患者的肥胖问题复杂化。其治疗需要皮肤科和专科泌尿外科的参与，可能具有挑战性，但却是有效的。这一现象增加了尿液的闭塞作用在MGLSc发病机制中起作用的证据。
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