De Anna D, Mari F, Intini S, Gasbarro V, Sortini A, Pozza E, Marzola R, Taddeo U, Bresadola F, Donini I
Minerva Cardioangiol. 1989 May;37(5):251-4.
Following a short introduction on the physiopathology of the phlebo-lymphatic system, the results of a study carried out on 114 patients suffering from chronic venous insufficiency (CVI) treated at the Department of General Clinical Surgery and Surgical Therapy of the University of Ferrara are reported. These patients were subdivided into two random groups and treated with common phlebotonic drugs and aminaftone, respectively. Both groups were also subjected to those physical and medical measures that are usually adopted for the treatment of such patients. The therapeutic effects were assessed by comparing symptomatology before and after 90 days of treatment, both subjectively (patient's assessment of the symptoms by means of a scoring system) and with objective methods (measurements and echo-Doppler examinations). The differences between the two groups were statistically very significant in favour of patients who had taken aminaftone. Excellent results were obtained in the treatment of CVI as well as in lymphatic-related pathology (lymphedema).
在对静脉 - 淋巴系统的生理病理学进行简短介绍之后,报告了一项针对114例慢性静脉功能不全(CVI)患者的研究结果,这些患者在费拉拉大学普通临床外科和外科治疗系接受治疗。这些患者被随机分为两组,分别用普通静脉活性药物和氨萘非特进行治疗。两组患者均接受了通常用于治疗此类患者的物理和医学措施。通过比较治疗90天前后的症状学来评估治疗效果,包括主观评估(患者通过评分系统对症状进行评估)和客观方法(测量和超声多普勒检查)。两组之间的差异在统计学上非常显著,有利于服用氨萘非特的患者。在CVI以及与淋巴相关的病理学(淋巴水肿)的治疗中均取得了优异的效果。