吸烟和年龄对腭黏膜角化的影响：一项细胞学研究。

Effects of tobacco smoking and age on the keratinization of palatal mucosa: a cytologic study.

作者信息

Mosadomi A, Shklar G, Loftus E R, Chauncey H H

出版信息

Oral Surg Oral Med Oral Pathol. 1978 Sep;46(3):413-7. doi: 10.1016/0030-4220(78)90407-3.

Abstract

Cytologic smears of palatal mucosa were evaluated for degree of keratinization in 217 healthy men ranging in age from 30 to 74 years. Two slides were prepared for each participant, and each slide was read by two different pathologists. Three separate high-power fields were examined on each slide, and the percentage of orange-brown cells, either without nuclei or with pyknotic or fragmented nuclei, was recorded. A mean value was obtained for each participant. Each participant had an extensive medical and dental work-up as part of the Veterans Administration Longitudinal Study of Oral Health in Healthy Veterans. Nonsmokers and smokers were divided into five age groups. Smokers at all ages presented a greater degree of palatal keratinization than nonsmokers, but age differences in keratinization were not statistically significant.

摘要

对217名年龄在30至74岁之间的健康男性的腭黏膜细胞涂片进行角化程度评估。为每位参与者制备两张玻片，每张玻片由两位不同的病理学家阅片。在每张玻片上检查三个独立的高倍视野，并记录无核、核固缩或核碎裂的橙褐色细胞的百分比。为每位参与者获得一个平均值。作为退伍军人管理局健康退伍军人口腔健康纵向研究的一部分，每位参与者都进行了全面的医学和牙科检查。非吸烟者和吸烟者被分为五个年龄组。所有年龄段的吸烟者腭部角化程度均高于非吸烟者，但角化程度的年龄差异无统计学意义。