Gabrielli Simona, Tasić-Otašević Suzana, Ignjatović Aleksandra, Fraulo Maurizio, Trenkić-Božinović Marija, Momčilović Stefan, Cancrini Gabriella
1 Department of Public Health and Infectious Diseases, "Sapienza" University of Rome , Rome, Italy .
2 Department of Microbiology and Immunology, Faculty of Medicine, University of Niš , Niš, Serbia .
Foodborne Pathog Dis. 2017 Jan;14(1):43-49. doi: 10.1089/fpd.2016.2190. Epub 2016 Nov 28.
We report data on the Toxocara seroprevalence evidenced in 2015 from samples of 40 children and 298 adults of the population living in different areas of Serbia, and on possible association of certain variables with infection. Detection of specific antibodies was performed using an enzyme-linked immunosorbent assay; all ambiguous results and part of the positive and negative sera were further analyzed by confirmatory Western blot test. An overall 23.5% seroprevalence was noticed, which was confirmed in 13.0% of the examined population with no significant difference regarding the age (children = 10.0%; adults = 13.4%) or by country area (East = 18.2%; North = 15.5%, Southeastern = 9.5%; p = 0.005). In contrast, the group of adult women proved more reactive than men (p = 0.001), and subjects both who spend spare time in square/parks (p = 0.041) and with positive onychophagy (p = 0.001) habit turned out more exposed to the infection. Possible reasons of these differences were analyzed, and the medical, veterinary, and economic impact of this soil-transmitted zoonosis were discussed.
我们报告了2015年从塞尔维亚不同地区的40名儿童和298名成年人样本中得出的弓蛔虫血清阳性率数据，以及某些变量与感染之间可能存在的关联。使用酶联免疫吸附测定法检测特异性抗体；所有不确定结果以及部分阳性和阴性血清通过确证性免疫印迹试验进一步分析。总体血清阳性率为23.5%，在13.0%的受检人群中得到证实，在年龄方面（儿童=10.0%；成年人=13.4%）或国家地区方面（东部=18.2%；北部=15.5%，东南部=9.5%；p=0.005）无显著差异。相比之下，成年女性组比男性组反应性更强（p=0.001），并且在广场/公园度过业余时间的受试者（p=0.041）和有咬甲癖阳性习惯的受试者（p=0.001）被证明更容易感染。分析了这些差异的可能原因，并讨论了这种土壤传播的人畜共患病的医学、兽医和经济影响。
