表现为未确诊疾病的免疫缺陷
Immunodeficiency Presenting as an Undiagnosed Disease.
作者信息
Routes John M, Verbsky James W
机构信息
Department of Pediatrics, Children's Research Institute, Medical College of Wisconsin, Children's Clinics Building, Suite B440, 9000 West Wisconsin Avenue, Milwaukee, WI 53226-4874, USA.
Department of Pediatrics, Children's Corporate Center, Children's Research Institute, Medical College of Wisconsin, Suite C465, 9000 West Wisconsin Avenue, Milwaukee, WI 53226-4874, USA.
出版信息
Pediatr Clin North Am. 2017 Feb;64(1):27-37. doi: 10.1016/j.pcl.2016.08.007.
Although primary immunodeficiencies typically present with recurrent, chronic, or severe infections, autoimmune manifestations frequently accompany these disorders and may be the initial clinical manifestations. The presence of 2 or more autoimmune disorders, unusual severe atopic disease, or a combination of these disorders should lead a clinician to consider primary immunodeficiency disorders.
虽然原发性免疫缺陷通常表现为反复、慢性或严重感染，但自身免疫表现常伴随这些疾病，且可能是最初的临床表现。存在两种或更多种自身免疫性疾病、异常严重的特应性疾病或这些疾病的组合，应促使临床医生考虑原发性免疫缺陷疾病。
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