Brauneis J, Schröder M, Laskawi R
Hals-Nasen-Ohren-Klinik der Universität Göttingen.
Laryngorhinootologie. 1989 Aug;68(8):442-4. doi: 10.1055/s-2007-998372.
It is well known that the incidence of malignant lymphomas (non-Hodgkin type) is increased in patients with Sjögren's syndrome. The occurrence of malignant diseases was retrospectively studied in 62 patients. In the course of the disease two patients developed a non-Hodgkin lymphoma, one patient developed a transitional-cell carcinoma located in the nasopharynx and three patients developed a squamous-cell carcinoma located in the salivary glands. The large quantity of epithelial carcinomas seems to be remarkable, especially compared with the number of non-Hodgkin lymphomas. It might be possible that early surgical treatment of persistent or progressive swelling of the salivary glands helps to prevent the occurrence of malignant lymphoma in patients with known myoepithelial sialadenitis.
众所周知，干燥综合征患者中恶性淋巴瘤（非霍奇金型）的发病率会升高。对62例患者的恶性疾病发生情况进行了回顾性研究。在疾病过程中，2例患者发生了非霍奇金淋巴瘤，1例患者发生了位于鼻咽部的移行细胞癌，3例患者发生了位于唾液腺的鳞状细胞癌。上皮癌的数量之多似乎很显著，尤其是与非霍奇金淋巴瘤的数量相比。对于已知患有肌上皮性涎腺炎的患者，对唾液腺持续性或进行性肿胀进行早期手术治疗可能有助于预防恶性淋巴瘤的发生。
