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血浆置换在有机磷中毒中的应用:一例报告。

Utilization of plasmapheresis for organophosphate intoxication: A case report.

作者信息

Disel Nezihat Rana, Acikalin Ayca, Kekec Zeynep, Sebe Ahmet

机构信息

Cukurova University, Faculty of Medicine, Department of Emergency Medicine, Adana, Turkey.

出版信息

Turk J Emerg Med. 2016 May 7;16(2):69-71. doi: 10.1016/j.tjem.2015.06.003. eCollection 2016 Jun.

Abstract

Organophosphate (OP) compounds are extremely toxic chemicals that may be absorbed via skin, conjunctiva, gastrointestinal and respiratory systems. Treatment of OP poisoning is a critical and aggressive process which includes decontamination, antidote administration (atropin and oximes), mechanical ventilation support and extracorporeal elimination procedures if needed. Here we present a young female patient who was unintentionally poisoned by an OP (trichlorfon) after using it to moisture her skin. The importance of this patient is the dermal disease that makes her unprotective to dermal exposure of chemicals and application of plasmapheresis to treat her poisoning.

摘要

有机磷酸酯(OP)化合物是剧毒化学品,可通过皮肤、结膜、胃肠道和呼吸系统吸收。OP中毒的治疗是一个关键且积极的过程,包括去污、使用解毒剂(阿托品和肟类)、机械通气支持以及必要时的体外清除程序。在此,我们介绍一名年轻女性患者,她在使用敌百虫(一种OP)滋润皮肤后意外中毒。该患者的特殊之处在于其皮肤病使她对皮肤接触化学品缺乏防护能力,以及采用血浆置换术治疗其中毒情况。

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本文引用的文献

8
The effect of plasmapheresis on plasma cholinesterase levels in a patient with organophosphate poisoning.
Hum Exp Toxicol. 2004 Jul;23(7):365-8. doi: 10.1191/0960327104ht462cr.
9
Current applications of plasmapheresis in clinical toxicology.血浆置换在临床毒理学中的当前应用。
Nephrol Dial Transplant. 2003 Jul;18 Suppl 5:v56-8. doi: 10.1093/ndt/gfg1049.
10
Therapeutic plasma exchange in the intensive care setting.重症监护环境下的治疗性血浆置换
Ther Apher. 2001 Oct;5(5):351-7. doi: 10.1046/j.1526-0968.2001.00383.x.

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