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[炎性肌病]

[Inflammatory myopathies].

作者信息

Maurer Britta

机构信息

Klinik für Rheumatologie, Universitätsspital Zürich, Gloriastr. 25, 8091, Zürich, Schweiz.

出版信息

Z Rheumatol. 2017 Feb;76(1):33-45. doi: 10.1007/s00393-016-0233-9.

Abstract

Inflammatory myopathies comprise heterogeneous, often multisystemic autoimmune diseases with muscle involvement as a common feature. The prognosis largely depends on a timely diagnosis and initiation of therapy. Given the complexity of these rare diseases, when an inflammatory myopathy is suspected patients should be referred to an expert center with established algorithms for the diagnostic work-up. The differential diagnostic exclusion of myositis mimics should ideally be carried out in close collaboration with neurologists and neuropathologists. The choice of immunosuppressive treatment should primarily depend on disease severity and organ involvement but age and comorbidities also have to be taken into account.

摘要

炎性肌病是一组异质性的、通常为多系统的自身免疫性疾病,肌肉受累是其共同特征。预后很大程度上取决于及时诊断和开始治疗。鉴于这些罕见疾病的复杂性,当怀疑患有炎性肌病时,患者应被转诊至拥有成熟诊断流程算法的专家中心。理想情况下,应与神经科医生和神经病理学家密切合作,对疑似肌炎的疾病进行鉴别诊断排除。免疫抑制治疗的选择应主要取决于疾病严重程度和器官受累情况,但年龄和合并症也必须考虑在内。

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