诊断：改善不明原发癌患者的诊断、治疗及预后。 - Suppr | 超能文献

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诊断：改善不明原发癌患者的诊断、治疗及预后。 - Suppr | 超能文献

Diagnosis: Improved diagnosis, therapy and outcomes for patients with CUP.

作者信息

Greco F Anthony

机构信息

Sarah Cannon Cancer Center, Tennessee Oncology, 250 25th Avenue North Suite 100, Nashville, Tennessee 37203, USA.

出版信息

Nat Rev Clin Oncol. 2017 Jan;14(1):5-6. doi: 10.1038/nrclinonc.2016.194. Epub 2016 Nov 29.

DOI:10.1038/nrclinonc.2016.194

Abstract

摘要

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Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis.基于表观遗传学特征对不明原发灶癌进行分类：一项多中心、回顾性分析。

Lancet Oncol. 2016 Oct;17(10):1386-1395. doi: 10.1016/S1470-2045(16)30297-2. Epub 2016 Aug 27.

2

Gene expression profiling identifies responsive patients with cancer of unknown primary treated with carboplatin, paclitaxel, and everolimus: NCCTG N0871 (alliance).基因表达谱分析可识别接受卡铂、紫杉醇和依维莫司治疗的原发灶不明癌症的反应性患者：NCCTG N0871（联盟研究）

Ann Oncol. 2016 Feb;27(2):339-44. doi: 10.1093/annonc/mdv543. Epub 2015 Nov 16.

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Poorly differentiated neoplasms of unknown primary site: diagnostic usefulness of a molecular cancer classifier assay.

Cancers (Basel). 2018 Apr 5;10(4):108. doi: 10.3390/cancers10040108.

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Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary.基于表观基因组学的精准医学：不明原发癌的范例。

Nat Rev Clin Oncol. 2017 Nov;14(11):682-694. doi: 10.1038/nrclinonc.2017.97. Epub 2017 Jul 4.

原发部位不明的低分化肿瘤：分子癌症分类检测的诊断价值

Mol Diagn Ther. 2015 Apr;19(2):91-7. doi: 10.1007/s40291-015-0133-8.

4

Occult primary, version 3.2014.隐匿性原发，版本 3.2014.

J Natl Compr Canc Netw. 2014 Jul;12(7):969-74. doi: 10.6004/jnccn.2014.0093.

5

Gene expression profiling in patients with carcinoma of unknown primary site: from translational research to standard of care.原发灶不明癌患者的基因表达谱分析：从转化研究到临床常规。

Virchows Arch. 2014 Apr;464(4):393-402. doi: 10.1007/s00428-014-1545-2. Epub 2014 Feb 1.

6

Carcinoma of unknown primary with gastrointestinal profile: immunohistochemistry and survival data for this favorable subset.具有胃肠道特征的原发性不明癌：这一预后良好亚组的免疫组化及生存数据

Int J Clin Oncol. 2014;19(3):479-84. doi: 10.1007/s10147-013-0583-0. Epub 2013 Jun 28.

7

Molecular profiling diagnosis in unknown primary cancer: accuracy and ability to complement standard pathology.不明原发肿瘤的分子谱诊断：准确性和对标准病理学的补充能力。

J Natl Cancer Inst. 2013 Jun 5;105(11):782-90. doi: 10.1093/jnci/djt099. Epub 2013 May 2.

8

Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients with carcinoma of unknown primary site: a prospective trial of the Sarah Cannon research institute.采用分子基因表达谱分析预测原发灶不明的癌患者的组织来源和直接靶向特定部位的治疗：萨拉·坎农研究所的一项前瞻性试验。

J Clin Oncol. 2013 Jan 10;31(2):217-23. doi: 10.1200/JCO.2012.43.3755. Epub 2012 Oct 1.

9

A retrospective study of treatment outcomes in patients with carcinoma of unknown primary site and a colorectal cancer molecular profile.回顾性研究具有结直肠癌分子特征的不明原发部位癌患者的治疗效果。

Clin Colorectal Cancer. 2012 Jun;11(2):112-8. doi: 10.1016/j.clcc.2011.08.001. Epub 2011 Oct 14.

10

Switching benchmarks in cancer of unknown primary: from autopsy to microarray.未知原发癌的基准转换：从尸检到微阵列。

Eur J Cancer. 2007 Sep;43(14):2026-36. doi: 10.1016/j.ejca.2007.06.023. Epub 2007 Aug 14.