Hart Robert A, Hiratzka Jayme, Kane Marie S, Lafage Virginie, Klineberg Eric, Ames Christopher P, Line Breton G, Schwab Frank, Scheer Justin K, Bess Shay, Hamilton David K, Shaffrey Christopher I, Mundis Greg, Smith Justin S, Burton Douglas C, Sciubba Daniel M, Deviren Vedat, Boachie-Adjei Oheneba
Oregon Health and Science University, Portland, OR.
Hospital for Special Surgery, New York, NY.
Spine (Phila Pa 1976). 2017 Aug 1;42(15):1151-1157. doi: 10.1097/BRS.0000000000002006.
Prospective, multicenter.
To determine if stiffness significantly affects function or satisfaction after pan-lumbar arthrodesis.
The Lumbar Stiffness Disability Index (LSDI) is a validated measure of the effect of lumbar stiffness on functional activities. Data suggests that patients undergoing fusion of the entire lumbar spine are at greatest risk of functional limitations from stiffness.
The LSDI, Short Form 36, Scoliosis Research Society-22, and Oswestry Disability Index were administered preoperatively and at 2-year minimum follow-up to 103 spinal deformity patients from 11 centers. Patients were separated according to the proximal arthrodesis level; upper thoracic (T2-5) to pelvis (UT-Pelvis) or thoraco-lumbar (T10-T12) to pelvis (TL-Pelvis). Outcome scores were compared using Student t test or Tukey-Kramer Honest Significant Difference Analysis of Variance. Regression analysis of final LSDI scores versus Scoliosis Research Society-22 Satisfaction scores was performed.
Mean ages, baseline values, and final scores of all outcome parameters were statistically equivalent in the two groups. Final LSDI scores did not change significantly from baseline in the UT-Pelvis (P = 0.478) or TL-Pelvis (P = 0.301) groups. In contrast, highly significant improvements (P ≤ 0.0001) from baseline were seen in both groups for other health-related QoL measures. The 2-year Satisfaction scores were statistically equivalent in the two groups, and the correlation between final LSDI and Satisfaction scores in the entire cohort was not significant (R = 0.013, P = 0.146).
Patients undergoing pan-lumbar arthrodesis for adult spinal deformity did not experience substantial increases in disability due to stiffness of the low back, although they did report significant improvements in other health-related QoL measures. Further, LSDI scores did not correlate with patient satisfaction. There were no significant differences in perceived stiffness effects whether arthrodesis stopped in the thoracolumbar or upper thoracic regions. We hope these results will be useful to spine surgeons and patients during preoperative planning and discussions.
前瞻性、多中心研究。
确定在全腰椎关节融合术后,僵硬是否会显著影响功能或满意度。
腰椎僵硬残疾指数(LSDI)是一种经过验证的衡量腰椎僵硬对功能活动影响的指标。数据表明,接受整个腰椎融合术的患者因僵硬导致功能受限的风险最大。
对来自11个中心的103例脊柱畸形患者在术前以及至少2年的随访期内进行腰椎僵硬残疾指数、简短健康调查问卷(SF-36)、脊柱侧弯研究学会-22项问卷(SRS-22)和奥斯威斯利残疾指数评估。患者根据近端融合水平进行分组;上胸椎(T2-5)至骨盆(UT-骨盆组)或胸腰椎(T10-T12)至骨盆(TL-骨盆组)。使用学生t检验或Tukey-Kramer诚实显著差异方差分析比较结果评分。对最终的腰椎僵硬残疾指数评分与脊柱侧弯研究学会-22项问卷满意度评分进行回归分析。
两组患者的平均年龄、基线值和所有结局参数的最终评分在统计学上相当。UT-骨盆组(P = 0.478)和TL-骨盆组(P = 0.301)的最终腰椎僵硬残疾指数评分与基线相比无显著变化。相比之下,两组患者在其他与健康相关的生活质量指标方面与基线相比均有高度显著改善(P≤0.0001)。两组患者的2年满意度评分在统计学上相当,并且整个队列中最终腰椎僵硬残疾指数评分与满意度评分之间的相关性不显著(R = 0.013,P = 0.146)。
接受成人脊柱畸形全腰椎关节融合术的患者并未因下腰部僵硬而导致残疾大幅增加,尽管他们确实报告在其他与健康相关的生活质量指标方面有显著改善。此外,腰椎僵硬残疾指数评分与患者满意度无关。无论融合术在胸腰段还是上胸段停止,在感知到的僵硬影响方面均无显著差异。我们希望这些结果在术前规划和讨论期间对脊柱外科医生和患者有用。
2级。