Grass Fabian, Cachemaille Matthieu, Blanc Catherine, Fournier Nicolas, Halkic Nermin, Demartines Nicolas, Hübner Martin
Department of Visceral Surgery, University Hospital CHUV, Bugnon 46, 1011, Lausanne, Switzerland.
Department of Anaesthesiology, University Hospital CHUV, Lausanne, Switzerland.
BMC Surg. 2016 Dec 1;16(1):78. doi: 10.1186/s12893-016-0194-6.
Immediate laparoscopic cholecystectomy is the accepted standard for the treatment of acute cholecystitis. The aim of the present study was to evaluate the feasibility of a standardized approach with tailored care maps for pre- and postoperative care by comparing pain, nausea and patient satisfaction after elective and emergent laparoscopic cholecystectomy.
From January 2014 until April 2015, data on pain and nausea management were prospectively recorded for all elective and emergency procedures in the department of visceral surgery. This prospective observational study compared consecutive laparoscopic elective vs. emergency cholecystectomies. Visual analogue scales (VAS) were used to measure pain, nausea, and satisfaction from recovery room until 96 hours postoperatively.
Final analysis included 168 (79%) elective cholecystectomies and 44 (21%) emergent procedures. Demographics (Age, gender, BMI and ASA-scores) were comparable between the 2 groups. In the emergency group, patients did not receive anxiolytic medication (0% vs.13%, p = 0.009) and less postoperative nausea and vomiting (PONV) prophylaxis (77% vs. 97% p = <0.001). Perioperative pain management was similar in terms of opioid consumption (median amount of fentanyl 450ug [IQR 350-500] vs. 450ug [375-550], p = 0.456) and wound infiltration rates (24% vs. 25%, p = 0.799). Postoperative consumption of paracetamol, metamizole and opiod medications were similar between the 2 groups. VAS scores for pain (p = 0.191) and nausea (p = 0.392) were low for both groups. Patient satisfaction was equally high in both clinical settings (VAS 8.5 ± 1.1 vs. 8.6 ± 1.1, p = 0.68).
A standardized pathway allows equally successful control of pain and nausea after both elective and emergency laparoscopic cholecystectomy. This study was retrospectively registered by March 01, 2016 in the following trial register: www.researchregistry.com (UIN researchregistry993).
急诊腹腔镜胆囊切除术是治疗急性胆囊炎公认的标准方法。本研究旨在通过比较择期和急诊腹腔镜胆囊切除术后的疼痛、恶心情况及患者满意度,评估采用标准化方法并制定术前术后护理流程图的可行性。
2014年1月至2015年4月,对普外科所有择期和急诊手术的疼痛及恶心管理数据进行前瞻性记录。这项前瞻性观察性研究比较了连续的腹腔镜择期胆囊切除术与急诊胆囊切除术。采用视觉模拟评分法(VAS)测量从恢复室到术后96小时的疼痛、恶心及满意度。
最终分析纳入168例(79%)择期胆囊切除术和44例(21%)急诊手术。两组的人口统计学特征(年龄、性别、体重指数和美国麻醉医师协会评分)具有可比性。急诊组患者未接受抗焦虑药物治疗(0%对13%,p = 0.009),术后恶心呕吐预防性用药较少(77%对97%,p = <0.001)。围手术期疼痛管理在阿片类药物用量(芬太尼中位用量450μg[四分位间距350 - 500]对450μg[375 - 550],p = 0.456)和伤口浸润率方面相似(24%对25%,p = 0.799)。两组术后对乙酰氨基酚、安乃近和阿片类药物的用量相似。两组的疼痛(p = 0.191)和恶心(p = 0.392)VAS评分均较低。两种临床情况下患者满意度同样较高(VAS 8.5±1.1对8.6±1.1,p = 0.68)。
标准化流程在择期和急诊腹腔镜胆囊切除术后对疼痛和恶心的控制同样成功。本研究于2016年3月1日在以下试验注册库进行回顾性注册:www.researchregistry.com(UIN researchregistry993)。