Ørts Lene Maria, Løkke Anders, Bjerregaard Anne-Louise, Maindal Helle Terkildsen, Sandbæk Annelli
Department of Public Health, Section for General Practice, Aarhus University, Bartholins Allé 2, 8000, Aarhus, Denmark.
Department of Respiratory Diseases, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus C, Denmark.
Trials. 2016 Dec 1;17(1):571. doi: 10.1186/s13063-016-1704-7.
Early detection of lung diseases can help to reduce their severity. Lung diseases are among the most frequently occurring and serious diseases worldwide; nonetheless, many patients remain undiagnosed. Preventive health checks including spirometry can detect lung diseases at early stages; however, recruitment for health checks remains a challenge, and little is known about what motivates the attendance. The aim of the study is to examine whether focused information on spirometry in the invitation compared to general information will impact the attendance rate in preventive health checks.
METHODS/DESIGN: This randomized, controlled trial tests the effect of information on spirometry embedded in the Check your Health Preventive Program (CHPP). The CHPP is an open-label, household cluster-randomized, controlled trial offering a preventive health check to 30- to -49-year-olds in a Danish municipality from 2012 to 2017 (n = 26,216). During 2015-2016, 4356 citizens aged 30-49 years will be randomized into two groups. The intervention group receives an invitation which highlights the value and contents of spirometry as part of a health check and information about lung diseases. The comparison group receives a standard invitation containing practical information and specifies the contents of the general health check. Outcomes are (1) differences in attendance rates measured by the proportion of citizens attending each of the two study groups and (2) proportion of persons at risk defined by smoking status and self-reported lung symptoms in the study groups. The proportion of participants with abnormal spirometry assessed at the preventive health check will be compared between the two study groups.
The results from the present study will inform future recruitment strategies to health checks. The developed material on content, value, and information about lung disease is feasible and transferable to other populations, making it easy to implement if effective.
ClinicalTrials.gov: NCT02615769 . Registered on 25 November 2015.
肺部疾病的早期检测有助于减轻其严重程度。肺部疾病是全球最常见且最严重的疾病之一；尽管如此，仍有许多患者未被诊断出来。包括肺活量测定在内的预防性健康检查能够在早期阶段检测出肺部疾病；然而，健康检查的招募工作仍然是一项挑战，对于促使人们参加检查的因素知之甚少。本研究的目的是检验与提供一般信息相比，在邀请函中重点提及肺活量测定信息是否会影响预防性健康检查的参与率。
方法/设计：这项随机对照试验测试了在“检查您的健康”预防性项目（CHPP）中嵌入的肺活量测定信息的效果。CHPP是一项开放标签、家庭整群随机对照试验，在2012年至2017年期间为丹麦一个自治市的30至49岁人群提供预防性健康检查（n = 26,216）。在2015 - 2016年期间，4356名30至49岁的公民将被随机分为两组。干预组收到的邀请函强调了肺活量测定作为健康检查一部分的价值和内容以及有关肺部疾病的信息。对照组收到的是包含实用信息并详细说明一般健康检查内容的标准邀请函。结果指标为：（1）通过两个研究组中每组公民的参与比例衡量的参与率差异；（2）根据吸烟状况和自我报告的肺部症状确定的研究组中高危人群的比例。将比较两个研究组中在预防性健康检查时肺活量测定异常的参与者比例。
本研究的结果将为未来健康检查的招募策略提供参考。所开发的关于肺部疾病的内容、价值和信息的材料是可行的，并且可推广到其他人群，如果有效则易于实施。
ClinicalTrials.gov：NCT02615769。于2015年11月25日注册。
