Yildirim Vedat, Pausch Niels Christian, Halama Dirk, Lübbers Heinz-Theo, Yildirim Ayhan
Department of Oral, Craniomaxillofacial and Facial Plastic Surgery, University Hospital of Leipzig, Liebigstr. 12, 04103, Leipzig, Germany.
Private Practice for Oral and Maxillofacial Surgery, Archstr. 12, 8400, Winterthur, Switzerland.
J Med Case Rep. 2016 Dec 1;10(1):341. doi: 10.1186/s13256-016-1114-1.
Sinonasal inverted papilloma is a locally aggressive tumor arising from the Schneiderian membrane which lines the nasal cavity and paranasal sinuses. Aggressive surgical approaches, such as lateral rhinotomy, were used until recently for complete removal of the inverted papilloma. Currently, endoscopic resection is the gold standard in the treatment of inverted papilloma. However, there are situations that justify an open approach. For example there are studies that report a higher postoperative recurrence rate after endonasal endoscopic resection, particularly in the treatment of recurrent diseases. While endoscopic resection performed by an experienced surgeon is definitely a minimally invasive therapy, an open approach is not necessarily associated with functional and aesthetic disadvantages. This case report describes the treatment of inverted papilloma by an open approach. This has been described before but the new gold standard of endoscopic resection has to be taken into account before any treatment decision is made nowadays.
Contrast-enhanced magnetic resonance imaging of the head and neck area was indicated in a 72-year-old white German man who presented with suspected squamous cell carcinoma of his lower lip. Magnetic resonance imaging additionally revealed a 3×2 cm polycyclic arranged mucosal thickening with cystic and solid contrast affine shares at the antral laterocaudal area of his right maxillary sinus, extending from his right lateral nasal wall to his maxillary sinus floor. He received antral polypectomy with medial maxillectomy via a unilateral LeFort I osteotomy approach. His pterygoid plate was preserved. A histological examination demonstrated a tumor composed of hyperplastic squamous epithelium protruding into the stroma (surface epithelial cells grew downward into the underlying supportive tissue), thus producing a grossly convoluted cerebriform appearance. Two weeks later, the patient regained a well-formed maxilla without any restrictions. He has remained disease-free for 25 months following the surgery and surveillance was continued in our tumor clinic.
Endoscopic resection of an inverted papilloma continues to be the gold standard. However, some cases require a radical approach. This does not necessarily increase patient morbidity.
鼻窦内翻性乳头状瘤是一种起源于鼻腔和鼻窦内衬的施奈德膜的局部侵袭性肿瘤。直到最近,诸如鼻侧切开术等激进的手术方法仍被用于完全切除内翻性乳头状瘤。目前,内镜切除术是治疗内翻性乳头状瘤的金标准。然而,在某些情况下开放手术也是合理的。例如,有研究报告称鼻内镜下切除术后复发率较高,尤其是在复发性疾病的治疗中。虽然经验丰富的外科医生进行的内镜切除术无疑是一种微创治疗方法,但开放手术并不一定会带来功能和美观方面的劣势。本病例报告描述了采用开放手术治疗内翻性乳头状瘤的情况。此前已有相关描述,但在如今做出任何治疗决策之前,都必须考虑到内镜切除术这一新的金标准。
一名72岁的德国白人男性因下唇疑似鳞状细胞癌接受了头颈部区域的对比增强磁共振成像检查。磁共振成像还显示,在其右上颌窦窦腔后外侧区域有一个3×2厘米的多环状排列的黏膜增厚区,伴有囊性和实性对比增强部分,从右侧鼻侧壁延伸至右上颌窦底部。他通过单侧勒福I型截骨术接受了鼻窦息肉切除术及上颌骨内侧切除术。翼突板得以保留。组织学检查显示肿瘤由增生的鳞状上皮突入间质组成(表面上皮细胞向下生长进入下方的支持组织),因此呈现出明显的脑回状外观。两周后,患者上颌骨恢复良好,没有任何限制。术后25个月他一直无病,仍在我们的肿瘤诊所接受监测。
内翻性乳头状瘤的内镜切除术仍然是金标准。然而,一些病例需要采取根治性方法。这不一定会增加患者的发病率。