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重度边缘型人格障碍患者的多重聚类轴II共病与功能结局

Multiple cluster axis II comorbidity and functional outcome in severe patients with borderline personality disorder.

作者信息

Palomares Nerea, McMaster Antonia, Díaz-Marsá Marina, de la Vega Irene, Montes Ana, Carrasco José Luis

机构信息

Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC). Madrid, Spain Centro de Investigación en Red de Salud Mental (CIBERSAM). Hospital Gregorio Marañón. Madrid, Spain.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai. New York.

出版信息

Actas Esp Psiquiatr. 2016 Nov;44(6):212-21. Epub 2016 Nov 1.

Abstract

BACKGROUND

Current literature suggests that personality disorder comorbidity negatively contributes to both the severity and prognosis of other disorders; however, little literature has been devoted to its influence on borderline personality disorder (BPD). The objective of the present work is to study comorbidity with other personality disorders in a severe clinical sample of patients with BPD, and its relationship with global functionality.

METHODS

A sample of 65 patients with severe borderline personality disorder was included in the study. Clinical and functionality measures were applied in order to study comorbidity of BPD with other disorders and its relationship with functionality. Associations with other comorbid PDs were analyzed with t-tests and linear correlations.

RESULTS

Most patients (87%) presented comorbidity with other PDs. Almost half of the sample (42%) presented more than two PDs, and cluster A (paranoid) and C (obsessive and avoidant) PD were more frequent than cluster B (histrionic and antisocial). Only the presence of avoidant PD predicted a worse functional outcome in the long term (U Mann Withney p<0.01).

CONCLUSIONS

Severely impaired BPD patients present greater comorbidity with cluster A and C PDs. Comorbid avoidant personality disorder might negatively predict for prognosis.

摘要

背景

当前文献表明,人格障碍合并症会对其他疾病的严重程度和预后产生负面影响;然而,关于其对边缘型人格障碍(BPD)影响的文献却很少。本研究的目的是在一组严重的BPD临床患者样本中,研究其与其他人格障碍的合并症情况,以及这种合并症与整体功能的关系。

方法

本研究纳入了65例患有严重边缘型人格障碍的患者样本。应用临床和功能测量方法,以研究BPD与其他疾病的合并症情况及其与功能的关系。通过t检验和线性相关性分析与其他共病性人格障碍的关联。

结果

大多数患者(87%)存在与其他人格障碍的合并症。几乎一半的样本(42%)存在两种以上的人格障碍,A组(偏执型)和C组(强迫型和回避型)人格障碍比B组(表演型和反社会型)更为常见。从长远来看,只有回避型人格障碍的存在预示着功能预后较差(U曼-惠特尼检验p<0.01)。

结论

严重受损的BPD患者与A组和C组人格障碍的合并症更为常见。共病的回避型人格障碍可能对预后产生负面影响。

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