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肺动脉高压和肥胖低通气综合征术后并发症谱

Spectrum of postoperative complications in pulmonary hypertension and obesity hypoventilation syndrome.

作者信息

Kaw Roop K

机构信息

Departments of Hospital Medicine and Anesthesiology Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA.

出版信息

Curr Opin Anaesthesiol. 2017 Feb;30(1):140-145. doi: 10.1097/ACO.0000000000000420.

Abstract

PURPOSE OF REVIEW

The purpose of this review is to identify chronic pulmonary conditions which may often not be recognized preoperatively especially before elective noncardiac surgery and which carry the highest risk of perioperative morbidity and mortality.

RECENT FINDINGS

This review discusses some of the most recent studies that highlight the perioperative complications, and their prevention and management strategies.

SUMMARY

Pulmonary hypertension is a well recognized risk factor for postoperative complications after cardiac surgery but the literature surrounding noncardiac surgery is sparse. Pulmonary hypertension was only recently classified as an independent risk factor for postoperative complications in the American Heart Association/American College of Cardiology Foundation Practice Guideline for noncardiac surgery. Spinal anesthesia should be avoided in most surgeries on patients with pulmonary hypertension because of it's rapid sympatholytic effects. The presence of significant right ventricle dysfunction and marked hypoxemia should prompt re-evaluation of the need for elective surgery. Obesity hypoventilation syndrome is even harder to recognize preoperatively as arterial blood gases are generally not obtained prior to elective noncardiac surgery. Amongst patients with obstructive sleep apnea this group of patients carries much higher risk of postoperative respiratory and congestive heart failure.

摘要

综述目的

本综述的目的是识别那些术前常常未被认识到的慢性肺部疾病,尤其是在择期非心脏手术前,以及那些围手术期发病率和死亡率风险最高的疾病。

最新研究发现

本综述讨论了一些突出围手术期并发症及其预防和管理策略的最新研究。

总结

肺动脉高压是心脏手术后公认的术后并发症危险因素,但关于非心脏手术的文献较少。在美国心脏协会/美国心脏病学会基金会非心脏手术实践指南中,肺动脉高压直到最近才被列为术后并发症的独立危险因素。由于其快速的交感神经阻滞作用,大多数肺动脉高压患者手术应避免使用脊髓麻醉。存在明显的右心室功能障碍和显著低氧血症时,应重新评估择期手术的必要性。肥胖低通气综合征术前更难识别,因为择期非心脏手术前一般不进行动脉血气分析。在阻塞性睡眠呼吸暂停患者中,这组患者术后呼吸和充血性心力衰竭的风险要高得多。

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