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前列腺癌根治术后手术阿普加评分与围手术期并发症之间的关联。

Association between the Surgical Apgar Score and Perioperative Complications after Radical Prostatectomy.

作者信息

Orberger Matthias, Palisaar Jüri, Roghmann Florian, Mittelstädt Ludger, Bischoff Petra, Noldus Joachim, Löppenberg Björn

机构信息

Department of Urology, Ruhr-University Bochum, Marien Hospital Herne, Herne, Germany.

出版信息

Urol Int. 2017;98(1):61-70. doi: 10.1159/000450795. Epub 2016 Dec 2.

Abstract

OBJECTIVE

To evaluate whether the Surgical Apgar Score (SAS) can identify patients who are at risk for perioperative adverse events (PAE) following radical prostatectomy for prostate cancer.

PATIENTS AND METHODS

At a single academic institution, 994 patients undergoing radical prostatectomy between 2010 and 2013 were analyzed retrospectively. The SAS was calculated from anesthesia records, evaluated to predict PAE within a 30-day time period postoperatively; these events were classified according to standardized classification systems.

RESULTS

We observed adverse events in 45.4% (451/994) of patients with a total of 694 events. Overall, 41% (408/994) had low- and 9.9% (98/994) had high-grade events. A lower SAS was identified as an independent predictor of any (p < 0.001) and low-grade adverse events (p = 0.001) for those patients who had undergone open retropubic radical prostatectomy (ORRP). Each 1-point increment resulted in a 24% decrease in the odds of any (95% CI 0.66-0.88) and a 21% decrease in the odds of a low-grade (95% CI 0.69-0.91) event. Adverse events of robot-assisted prostatectomy were not associated with the SAS.

CONCLUSIONS

Lower SAS values indicate patients at risk for adverse events after ORRP. The SAS might serve as one variable for outcome assessment, reflecting the challenge of mutual surgical and anesthesiology procedure management.

摘要

目的

评估手术阿普加评分(SAS)能否识别出前列腺癌根治性前列腺切除术后围手术期不良事件(PAE)风险较高的患者。

患者与方法

在一家学术机构,对2010年至2013年间接受根治性前列腺切除术的994例患者进行回顾性分析。根据麻醉记录计算SAS,评估其预测术后30天内PAE的能力;这些事件按照标准化分类系统进行分类。

结果

我们观察到45.4%(451/994)的患者发生了不良事件,共计694起事件。总体而言,41%(408/994)的患者发生低级别事件,9.9%(98/994)的患者发生高级别事件。对于接受耻骨后根治性前列腺切除术(ORRP)的患者,较低的SAS被确定为任何不良事件(p < 0.001)和低级别不良事件(p = 0.001)的独立预测因素。SAS每增加1分,任何不良事件的发生几率降低24%(95%CI 0.66 - 0.88),低级别不良事件的发生几率降低21%(95%CI 0.69 - 0.91)。机器人辅助前列腺切除术的不良事件与SAS无关。

结论

较低的SAS值表明ORRP术后患者发生不良事件的风险较高。SAS可作为结果评估的一个变量,反映手术与麻醉相互管理的挑战。

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