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极低出生体重儿的抗生素暴露与死亡或支气管肺发育不良风险

Antibiotic Exposure and Risk for Death or Bronchopulmonary Dysplasia in Very Low Birth Weight Infants.

作者信息

Cantey Joseph B, Huffman Landon W, Subramanian Abirami, Marshall Anderson S, Ballard A Rebecca, Lefevre Cassandra, Sagar Malvika, Pruszynski Jessica E, Mallett Lea H

机构信息

Department of Pediatrics, Texas A&M Health Science Center, Baylor Scott & White Health, Temple, TX.

Department of Pediatrics, Texas A&M Health Science Center, Baylor Scott & White Health, Temple, TX.

出版信息

J Pediatr. 2017 Feb;181:289-293.e1. doi: 10.1016/j.jpeds.2016.11.002. Epub 2016 Nov 28.

DOI:10.1016/j.jpeds.2016.11.002
PMID:27908652
Abstract

We assessed the association between antibiotic exposure in the first 2 weeks of life and development of bronchopulmonary dysplasia in a cohort of very low birth weight infants. After controlling for the severity of illness, each additional day of antibiotic therapy was associated with both an increased risk for and severity of bronchopulmonary dysplasia.

摘要

我们评估了极低出生体重婴儿队列中出生后前2周内抗生素暴露与支气管肺发育不良发生之间的关联。在控制疾病严重程度后，抗生素治疗每增加一天，支气管肺发育不良的风险和严重程度均增加。

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