[The effect of the hemocoagulation status in hemodialyzed patients on the patency of arteriovenous fistulas].

In a group of regularly haemodialyzed patients the authors examined 15 who suffered from repeated obliterations of subcutaneous a-v fistulae and compared the results with findings in 14 patients before the establishment of the first fistula which did not become obliterated for a period of six months. The group of patients with repeated obliterations had a significantly lower level of antithrombin III, a higher number of thrombocytes with an increased aggregation induced by low concentrations of adenosine diphosphate and adrenaline. The authors assume that investigation of coagulation mechanisms in frequent obliterations of subcutaneous a-v fistulae can help towards therapeutic prevention and as a model situation for the investigation of the development of thrombosis in general.