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在一名患有暴发性心肌炎的6岁儿童中使用离心泵进行双心室支持。

Biventricular support using a centrifugal pump in a 6 year old with fulminant myocarditis.

作者信息

Kehara Hiromu, Takano Tamaki, Terasaki Takamitsu, Okada Kenji

机构信息

The Department of Cardiovascular Surgery, Suwa Red Cross Hospital, 5-11-50 Kogandori, Suwa, Nagano, 392-8510, Japan.

The Department of Cardiovascular Surgery, Nagano Red Cross Hospital, 5-22-1 Wakasato, Nagano, Nagano, 380-8582, Japan.

出版信息

J Artif Organs. 2017 Jun;20(2):166-169. doi: 10.1007/s10047-016-0939-0. Epub 2016 Dec 1.

Abstract

We experienced a case of ventricular assist with both a pulsatile-flow and a continuous-flow pump in a pediatric patient, and herein report the clinical course and characteristics of the pumps. A 6-year-old female was diagnosed with fulminant myocarditis and transferred to our hospital for mechanical support. After 12 days of extracorporeal membrane oxygenation, we implanted a left ventricular assist device (LVAD) and a right ventricular assist device (RVAD) using centrifugal Gyro pumps with a membrane oxygenator in a paracorporeal fashion. The membrane oxygenator was removed on postoperative day (POD) 4, and the patient was weaned from the respirator on POD 6. The LVAD was exchanged on POD 13 and 17, and the RVAD was exchanged on POD 14 because of thrombus formation inside the pumps. The RVAD was removed on POD 25. On POD 32, the patient experienced cerebral infarction and the centrifugal Gyro pump was switched to an extracorporeal pulsatile pump. No thromboembolic event occurred after pump conversion, although continuous administration of vasodilators was required to avoid hypertension. She underwent successfully heart transplantation in the USA after 8 months of ventricular support. A centrifugal pump is considered useful for pediatric patients, as pump flow and blood pressure can be relatively easily controlled in the postoperative acute phase compared with the pulsatile pump. However, special care should be taken to monitor for thrombus formation when support length becomes longer than 13 days, and a switch to a pulsatile pump should be considered once the hemodynamic status stabilizes.

摘要

我们遇到了一例儿科患者同时使用搏动流泵和连续流泵进行心室辅助的病例,在此报告泵的临床过程和特点。一名6岁女性被诊断为暴发性心肌炎并转至我院接受机械支持。在进行了12天的体外膜肺氧合后,我们以体外方式使用带膜式氧合器的离心式Gyro泵植入了左心室辅助装置(LVAD)和右心室辅助装置(RVAD)。术后第4天移除膜式氧合器,患者在术后第6天脱机。由于泵内形成血栓,LVAD在术后第13天和第17天进行了更换,RVAD在术后第14天进行了更换。RVAD在术后第25天被移除。术后第32天,患者发生脑梗死,离心式Gyro泵被切换为体外搏动泵。尽管需要持续使用血管扩张剂以避免高血压,但泵转换后未发生血栓栓塞事件。在心室支持8个月后,她在美国成功接受了心脏移植。与搏动泵相比,离心泵在术后急性期的泵流量和血压相对容易控制,因此被认为对儿科患者有用。然而,当支持时间超过13天时,应特别注意监测血栓形成,一旦血流动力学状态稳定,应考虑切换为搏动泵。

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