Despeghel Anne-Sophie, Mus Lisabeth, Dick Catherine, Vlaminck Stephan, Kuhweide Rudolf, Lerut Bob, Speleman Kato, Vinck Anne-Sophie, Vauterin Tom
AZ Sint-Jan BrugesRuddershove 10, 8000, Brugge, Belgium.
Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1665-1670. doi: 10.1007/s00405-016-4395-5. Epub 2016 Dec 1.
Our aim was to evaluate the long-term objective and subjective results of a modified expansion sphincter pharyngoplasty (ESP) technique in patients with sleep-disordered breathing. Single center prospective study of 35 patients underwent an ESP as a primary surgical treatment between June 2012 and September 2015 at the hospital AZ Sint-Jan Bruges-Ostend. Patients were divided into non-OSAS and OSAS (AHI >5). Primary outcome parameters were the Epworth Sleeping Scale (ESS, reduction and score less then 10) and the Visual Analogue Score of snoring (VAS, assessed by partner) evaluated at 3 months and 1 year. In addition, the OSAS group underwent a polysomnography after 6 months to calculate the Apneu-Hypopneu Index (AHI) change. Secondary outcome parameters were possible complications and morbidity rate. The overall Epworth Sleepiness Scale showed a steady total reduction of, respectively, 42 and 48% at the two timepoints. All patients had a post-operative score of less than ten points. The Visual Analogue Score improved in 92% of the patients; of these, the snoring was reduced in 86% and disappeared in 6%. In the OSAS group, we noticed a reduction in AHI of more than 50 in 53% of the patients. A considerable reduction was found in the severe OSAS group, where we found a mean pre-operative average AHI of 41.3/h that was reduced 6 months after the operation to 17.4/h. There were no severe complications or increased morbidity rate observed. This first long-term study shows that the modified ESP seems to be a safe and promising technique in palatal surgery for patients with sleep-disordered breathing. Surgical effectiveness is sustained after 1 year, both in OSAS as in snoring pathology. The technique seems as approachable for the basic ENT surgeon as the uvulopalatopharynoplasty.
我们的目的是评估改良的扩张性咽括约肌成形术(ESP)技术在睡眠呼吸障碍患者中的长期客观和主观效果。对2012年6月至2015年9月期间在AZ Sint-Jan Bruges-Ostend医院接受ESP作为主要手术治疗的35例患者进行单中心前瞻性研究。患者分为非阻塞性睡眠呼吸暂停低通气综合征(OSAS)组和OSAS组(呼吸暂停低通气指数[AHI]>5)。主要结局参数为3个月和1年时评估的爱泼华嗜睡量表(ESS,降低且得分低于10分)和由伴侣评估的鼾声视觉模拟评分(VAS)。此外,OSAS组在6个月后进行多导睡眠图检查以计算呼吸暂停低通气指数(AHI)的变化。次要结局参数为可能的并发症和发病率。总体爱泼华嗜睡量表在两个时间点分别稳定降低了42%和48%。所有患者术后评分均低于10分。92%的患者鼾声视觉模拟评分有所改善;其中,86%的患者鼾声降低,6%的患者鼾声消失。在OSAS组中,我们注意到53%的患者AHI降低超过50。在重度OSAS组中发现有相当大的降低,我们发现术前平均AHI为41.3次/小时,术后6个月降至17.4次/小时。未观察到严重并发症或发病率增加。这项首次长期研究表明,改良的ESP似乎是一种用于睡眠呼吸障碍患者腭部手术的安全且有前景的技术。在OSAS和打鼾病理方面,手术效果在1年后仍得以维持。该技术对于普通耳鼻喉科医生而言似乎与悬雍垂腭咽成形术一样易于操作。