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扩张咽缩肌成形术治疗阻塞性睡眠呼吸暂停:15 年回顾。

Expansion sphincter pharyngoplasty in OSA: a 15 year review.

机构信息

University of Glasgow, Glasgow, Scotland, UK.

Otorhinolaryngology, Asia Sleep Centre, Paragon Medical Centre, Singapore, Singapore.

出版信息

Eur Arch Otorhinolaryngol. 2023 Jul;280(7):3337-3344. doi: 10.1007/s00405-023-07901-5. Epub 2023 Mar 2.

Abstract

OBJECTIVE

A 15 year review of the outcomes and success rates of the Expansion Sphincter Pharyngoplasty (ESP) in the treatment of patients with obstructive sleep apnea (OSA).

METHODS

A systemic review with two independent searches of MEDLINE, Google Scholar, Cochrane Library and Evidence-Based Medicine Reviews to identify publications relevant to OSA and Expansion Pharyngoplasty. All relevant studies published before 31 December 2021 were included.

RESULTS

Sixteen studies were included in this strict systematic review with a total of 747 patients who had the ESP procedure were included. The mean age was 41.3 years, mean BMI 28.2, the mean pre-op AHI was 32.3 and post-op AHI was 10.0 (p < 0.05), the mean pre-op ESS was 11.4, had reduced to post-op 5.3 (p < 0.05), and the mean pre-op snore VAS decreased from 8.7 to 2.9 (p < 0.05), with a mean follow-up time of 9.5 months. The overall pooled success rate for all the 747 patients was 80.0%. There were no significant reported complications noted in these studies.

CONCLUSION

After 15 years of presence, the expansion sphincter pharyngoplasty has shown to be reliably effective in the management of patients with OSA.

摘要

目的

对 15 年来扩张咽缩肌成形术(ESP)治疗阻塞性睡眠呼吸暂停(OSA)患者的结果和成功率进行回顾。

方法

对 MEDLINE、Google Scholar、Cochrane 图书馆和循证医学评论进行了两次独立搜索,以查找与 OSA 和扩张咽成形术相关的出版物。纳入了截至 2021 年 12 月 31 日之前发表的所有相关研究。

结果

这项严格的系统评价纳入了 16 项研究,共有 747 例接受 ESP 手术的患者。平均年龄为 41.3 岁,平均 BMI 为 28.2,术前 AHI 平均为 32.3,术后 AHI 为 10.0(p<0.05),术前 ESS 平均为 11.4,术后为 5.3(p<0.05),术前打鼾 VAS 平均从 8.7 降至 2.9(p<0.05),平均随访时间为 9.5 个月。747 例患者的总体总成功率为 80.0%。这些研究中没有报告明显的并发症。

结论

扩张咽缩肌成形术存在 15 年后,已被证明在 OSA 患者的管理中是可靠有效的。

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