Neri Alessandro, Marrelli Daniele, Voglino Costantino, Di Mare Giulio, Ferrara Francesco, Marini Mario, Roviello Franco
Department of Medicine, Surgery and Neurosciences - Unit of General Surgery and Surgical Oncology, University of Siena, Viale Bracci - Policlinico "Le Scotte" 53100, Siena, Italy.
Department of Medicine, Surgery and Neurosciences - Unit of General Surgery and Surgical Oncology, University of Siena, Viale Bracci - Policlinico "Le Scotte" 53100, Siena, Italy.
Surg Oncol. 2016 Dec;25(4):355-363. doi: 10.1016/j.suronc.2016.08.003. Epub 2016 Aug 16.
Recurrent esophago-gastric junction adenocarcinoma is not a rare event and its correct management is still debated. Many approaches for the treatment of these patients exist, but only few studies compare the different techniques. Most of the studies are retrospectives series and describe the experiences of single institutions in the treatment of recurrent esophageal and esophago-gastric junction cancers. Nowadays surgery is still the main and only curative treatment. Other alternative palliative therapies could be endoscopic stent placement and balloon dilation, photodynamic therapy, thermal tumor ablation (laser photoablation and Argon plasma coagulation), radiation therapy and brachytherapy, and chemotherapy. The aim of this review is to investigate the different rates, patterns and timings of recurrence of this tumor, and to explain the various approaches used for the treatment of recurrent esophago-gastric junction cancer.
复发性食管胃交界腺癌并非罕见事件，其正确的治疗方法仍存在争议。针对这些患者有多种治疗方法，但只有少数研究比较了不同技术。大多数研究是回顾性系列研究，描述了单一机构在治疗复发性食管癌和食管胃交界癌方面的经验。如今，手术仍然是主要且唯一的根治性治疗方法。其他替代性姑息治疗方法包括内镜支架置入和球囊扩张、光动力疗法、热肿瘤消融（激光光凝和氩等离子体凝固）、放射治疗和近距离放射治疗以及化疗。本综述的目的是研究该肿瘤复发的不同发生率、模式和时间，并解释用于治疗复发性食管胃交界癌的各种方法。
