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土耳其肺部典型类癌肿瘤的支气管镜切除结果。

Results of bronchoscopic excision in typical carcinoid tumors of the lung in Turkey.

作者信息

Boyacı Hilal, Çörtük Mustafa, Gül Şule, Tanrıverdi Elif, Özgül Mehmet Akif, Dinçer Hüseyin Erhan, Çetinkaya Erdoğan

机构信息

Department of Chest Disease, Merzifon Karamustafa Paşa State Hospital, Amasya; Turkey.

Department of Chest Disease, Karabuk University Medical School, Karabuk; Turkey.

出版信息

Med Glas (Zenica). 2017 Feb 1;14(1):61-66. doi: 10.17392/881-16.

Abstract

Aim Carcinoid tumors of the lung are the tumors originating from the neuroendocrine cells. Surgical excision remains the gold standard for the treatment. Treatment with interventional bronchoscopic excision has also been reported as an alternative option in typical carcinoid tumors of the lung. The aim of this study was to present results and outcomes in patients who were bronchoscopically treated and followed-up. Methods Data of 14 patients, who had undergone bronchoscopic excision due to typical carcinoid tumor of the lung between April 2008 and July 2015 were retrospectively evaluated. Bronchoscopic excision procedures were performed under general anesthesia, while control bronchoscopies were carried out with flexible bronchoscopy. Time between the first and last bronchoscopies was accepted as the follow-up duration. Results A total of 14 patients was evaluated with eight (57.1%) males. Mean age was 43.57±14.07 (23-68) years. The most common symptoms were shortness of breath and coughing. Mean of 5.69±3.35 (2-12) bronchoscopy procedures were performed in the patients during the diagnosis, treatment and follow-up. Mean follow-up duration was 32.0±19.22 months. At the long-term follow-up, two patients developed 50% stenosis and one patient developed granulation tissue in the endobronchial treatment site. None of the patients developed recurrence during the mean.

摘要

目的 肺类癌肿瘤是起源于神经内分泌细胞的肿瘤。手术切除仍然是治疗的金标准。据报道,介入性支气管镜切除治疗也是肺典型类癌肿瘤的一种替代选择。本研究的目的是呈现接受支气管镜治疗并随访的患者的结果和转归。方法 回顾性评估2008年4月至2015年7月期间因肺典型类癌肿瘤接受支气管镜切除的14例患者的数据。支气管镜切除手术在全身麻醉下进行,而对照支气管镜检查采用柔性支气管镜。首次和末次支气管镜检查之间的时间被视为随访时间。结果 共评估了14例患者,其中8例(57.1%)为男性。平均年龄为43.57±14.07(23 - 68)岁。最常见的症状是呼吸急促和咳嗽。患者在诊断、治疗和随访期间平均接受了5.69±3.35(2 - 12)次支气管镜检查。平均随访时间为32.0±19.22个月。在长期随访中,2例患者出现50%的狭窄,1例患者在支气管内治疗部位出现肉芽组织。平均随访期间无患者出现复发。

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