Han Shuang, Li Bingqian, Song Ze, Pan Sihao, Zhang Zhichao, Yao Hui, Zhu Shuyun, Xu Guobao
College of Applied Chemistry, Shenyang University of Chemical Technology, Shenyang 110142, China.
Shandong Provincial Key Laboratory of Life Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165, China.
Analyst. 2016 Dec 19;142(1):218-223. doi: 10.1039/c6an02338j.
A single-walled carbon nanohorn (SWCNH) has been used to construct a molecularly imprinted electrochemical sensor for the first time. Kanamycin, a widely used aminoglycoside antibiotic, is used as a representative analyte to test the detection strategy. The kanamycin sensor was constructed by the electropolymerization of a molecularly imprinted poly-o-phenylenediamine film on a SWCNH modified glassy carbon electrode. The sensor was investigated in the presence or absence of kanamycin by cyclic voltammetry to verify the changes in the redox peak currents of KFe(CN). The sensor exhibits a linear range of 0.1-50 μM with a detection limit of 0.1 μM. It also shows high recognition ability, indicating that the SWCNH-based molecularly imprinted sensor is promising.
首次使用单壁碳纳米角（SWCNH）构建了分子印迹电化学传感器。卡那霉素是一种广泛使用的氨基糖苷类抗生素，用作代表性分析物来测试检测策略。通过在SWCNH修饰的玻碳电极上电聚合分子印迹聚邻苯二胺膜构建了卡那霉素传感器。通过循环伏安法在有或没有卡那霉素的情况下对该传感器进行研究，以验证铁氰化钾氧化还原峰电流的变化。该传感器的线性范围为0.1 - 50 μM，检测限为0.1 μM。它还表现出高识别能力，表明基于SWCNH的分子印迹传感器具有前景。
