[脾脏体液因子对大鼠实验性中毒性肝炎肝组织和血清胆碱酯酶活性的影响]
[Effect of splenic humoral factors on the cholinesterase activity of liver tissue and blood serum in experimental toxic hepatitis in rats].
作者信息
Shevchenko A V, Korpachev V V, Tychinin V A
出版信息
Fiziol Zh (1978). 1989 Jul-Aug;35(4):24-7.
PMID:2792437
Abstract
Activity of cholinesterase in the liver of rats with experimental toxic hepatitis decreases, while in the serum it remains unchanged. Introduction of splenin, a spleen preparation, normalizes indices of the cholinesterase activity, extract of muscles possessing no such property. Boiling-heated spleen preparation looses its activity. Activity of the studied enzyme remains unchanged both after splenectomy and splenin introduction to intact animals.
摘要
实验性中毒性肝炎大鼠肝脏中的胆碱酯酶活性降低，而血清中的胆碱酯酶活性保持不变。脾脏制剂脾宁的引入可使胆碱酯酶活性指标恢复正常，而肌肉提取物则无此特性。经煮沸加热的脾脏制剂会失去其活性。在对完整动物进行脾切除和引入脾宁后，所研究酶的活性均保持不变。
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