Jackstadt Rene, Sansom Owen James
CRUK Beatson Institute, University of Glasgow, Glasgow, UK.
EMBO J. 2017 Jan 4;36(1):3-4. doi: 10.15252/embj.201695973. Epub 2016 Dec 8.
Accurate wound repair is a crucial step to protect organisms from environmental damage, for example infection and toxin exposure. In this issue of , Miyoshi (2017) have elucidated a new mechanism underpinning this process within the intestine where mesenchymal prostaglandin E2 produced following damage drives intestinal regeneration.
精确的伤口修复是保护生物体免受环境损伤(如感染和毒素暴露)的关键步骤。在本期杂志中,Miyoshi(2017年)阐明了肠道内这一过程的一种新机制,即损伤后产生的间充质前列腺素E2驱动肠道再生。