Institute of Organic Chemistry, Polish Academy of Sciences , Kasprzaka 44/52, P.O. Box 58, 01-224 Warsaw, Poland.
Org Lett. 2016 Dec 2;18(23):6196-6199. doi: 10.1021/acs.orglett.6b03254. Epub 2016 Nov 15.
Selective transfer semihydrogenation of alkynes to yield alkenes was achieved with commercial first and second generation Hoveyda-Grubbs catalysts and formic acid as a hydrogen donor. This catalytic system is distinguished by its selectivity and compatibility with many functional groups (halogens, cyano, nitro, sulfide, alkenes). The metathetic activity of the ruthenium catalysts may be utilized in tandem sequences of olefin metathesis plus alkyne reduction.
使用商业第一代和第二代 Hoveyda-Grubbs 催化剂和甲酸作为氢供体，实现了炔烃的选择性半氢化转移生成烯烃。该催化体系具有选择性高、与多种官能团（卤素、氰基、硝基、硫醚、烯烃）相容性好的特点。钌催化剂的复分解活性可用于烯烃复分解加炔烃还原的串联序列。
