Stoll Dwight R, Carr Peter W
Department of Chemistry, Gustavus Adolphus College , Saint Peter, Minnesota 56082, United States.
Department of Chemistry, University of Minnesota , Minneapolis, Minnesota 55104, United States.
Anal Chem. 2017 Jan 3;89(1):519-531. doi: 10.1021/acs.analchem.6b03506. Epub 2016 Dec 9.
In this tutorial, we discuss the motivations for doing two-dimensional liquid chromatography (2D-LC) and describe the commonly used implementations of the method. We review important guiding principles for method development, discuss the state of the art in 2D-LC performance as measured by peak capacity, and describe example applications from different fields that we hope will inspire new users to adopt 2D-LC for their analytical problems.
在本教程中，我们将讨论进行二维液相色谱（2D-LC）分析的动机，并描述该方法常用的实现方式。我们回顾了方法开发的重要指导原则，讨论了以峰容量衡量的二维液相色谱性能的当前水平，并介绍了来自不同领域的示例应用，希望能激励新用户采用二维液相色谱来解决他们的分析问题。
