Ruben Jan, Truin Gert-Jan, Bronkhorst Ewald M, Huysmans Marie Charlotte D N J M
Department of Dentistry, Preventive and Restorative Dentistry, Radboud University Medical Center, Thomas van Aquinostraat 4, 6525 GD Nijmegen, The Netherlands.
J Dent. 2017 Feb;57:32-37. doi: 10.1016/j.jdent.2016.12.002. Epub 2016 Dec 7.
To develop an in situ model for erosive wear research which allows for more clinically relevant exposure parameters than other in situ models and to show tooth site-specific erosive wear effect of an acid challenge of orange juice on enamel.
This pilot study included 6 edentulous volunteers wearing full dentures with 13 embedded enamel samples The study consisted of two control runs: habitual diet only for 30days, and two experimental runs: habitual diet plus 125ml orange juice four times per day (consumed over 4m). In the first experimental run subjects were instructed to take the drink in their mouth and promptly swallow it. In the second experimental run subjects take the drink in their mouth and hold each 25ml for 30s, moving it around their mouth before swallowing. Sample enamel surface loss was measured using non-contact surface profilometry.
Drinking of orange juice additional to the habitual diet, caused significant but low increased erosive wear at buccal, palatal and lingual specimens. Significantly higher levels of tissue loss were found on all surfaces in the swishing experiment but molars (especially occlusal specimens in mandibular molars), palatal specimens sited in upper anterior teeth and lingual specimens in lower anterior teeth were most affected.
The model showed clinically relevant patterns of erosive tooth wear as seen clinically in erosive wear patients.
The model could have many applications to study clinically erosive wear for specific diets or consumption patterns and to test preventive measures.
建立一种用于侵蚀性磨损研究的原位模型，该模型比其他原位模型具有更符合临床实际的暴露参数，并展示橙汁酸刺激对牙釉质的牙齿部位特异性侵蚀性磨损效应。
这项初步研究纳入了6名佩戴全口义齿并嵌入13个牙釉质样本的无牙颌志愿者。该研究包括两个对照阶段：仅进行30天的习惯饮食，以及两个实验阶段：习惯饮食加上每天四次饮用125毫升橙汁（在4分钟内喝完）。在第一个实验阶段，受试者被要求将饮料含在口中并立即吞咽。在第二个实验阶段，受试者将饮料含在口中，每次25毫升保持30秒，在吞咽前在口腔中移动。使用非接触式表面轮廓仪测量样本牙釉质表面损失。
在习惯饮食之外饮用橙汁，导致颊侧、腭侧和舌侧样本的侵蚀性磨损显著但轻微增加。在漱口实验中，所有表面的组织损失水平均显著更高，但磨牙（尤其是下颌磨牙的咬合面样本）、上前牙的腭侧样本和下前牙的舌侧样本受影响最大。
该模型显示出在侵蚀性磨损患者临床中所见的符合临床实际的侵蚀性牙齿磨损模式。
该模型可用于研究特定饮食或消费模式的临床侵蚀性磨损，并测试预防措施。
