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输卵管异位妊娠干预的个体化:历史视角与异位妊娠的现代循证管理

Individualisation of intervention for tubal ectopic pregnancy: historical perspectives and the modern evidence based management of ectopic pregnancy.

作者信息

Odejinmi Funlayo, Huff Keren O, Oliver Reeba

机构信息

Whipps Cross University Hospital, Barts Health NHS Trust, London, E11 1NR, UK.

Whipps Cross University Hospital, Barts Health NHS Trust, London, E11 1NR, UK.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2017 Mar;210:69-75. doi: 10.1016/j.ejogrb.2016.10.037. Epub 2016 Oct 29.

DOI:10.1016/j.ejogrb.2016.10.037
PMID:27940397
Abstract

Historically, ectopic pregnancy was a life-threatening condition where diagnosis was possible only at post mortem or laparotomy and maternal mortality was up to 90%. The evolution in the management of ectopic pregnancy has meant that diagnosis can be made using non-invasive techniques with an aim to identify the ectopic gestation before tubal rupture. This enables health care professionals to offer management options that consider not only maternal mortality, but morbidity and fertility outcomes as well. In spite of this, diagnostic techniques and management options are not without limitations. Research is currently focused on new tests with a single diagnostic capability, diagnostic and treatment algorithms and safe methods of triaging patients. This article aims to review the current literature on the diagnosis and management of ectopic pregnancy and to formulate a pathway to help individualise care and achieve the best possible outcome.

摘要

从历史上看,异位妊娠是一种危及生命的疾病,只有在尸检或剖腹手术时才能确诊,孕产妇死亡率高达90%。异位妊娠管理方法的演变意味着可以使用非侵入性技术进行诊断,目的是在输卵管破裂前识别异位妊娠。这使得医疗保健专业人员能够提供不仅考虑孕产妇死亡率,还考虑发病率和生育结局的管理方案。尽管如此,诊断技术和管理方案并非没有局限性。目前的研究集中在具有单一诊断能力的新测试、诊断和治疗算法以及对患者进行安全分诊的方法上。本文旨在综述当前关于异位妊娠诊断和管理的文献,并制定一条途径,以帮助实现个性化护理并取得尽可能好的结果。

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