Suppr超能文献

[关于骨质疏松症治疗与心血管疾病相互作用的当前观点]

[Current views on the interaction between the treatment of osteoporosis and cardiovascular diseases].

作者信息

Zapolski Tomasz, Wysokiński Andrzej

机构信息

Katedra i Klinika Kardiologii, Uniwersytet Medyczny, Lublin, e-mail:

Katedra i Klinika Kardiologii, Uniwersytet Medyczny, Lublin.

出版信息

Wiad Lek. 2016;69(4):665-674.

Abstract

The most common medical conditions after menopause are osteoporosis and atherosclerotic disease. Traditionally these two conditions were considered unrelated and their coexistence has been attributed to independent processess exclusively reated to age. The possible link between cardiovascular disease and osteoporosis stimulates today to analyse not only the evidence of a possible association, but also to identify mutual beneficial and adverse effects of drugs used in these two diseases. That's why, the focus on the interference between osteoporosis treatment and drugs used for atherosclerosis is made. Moreover side effects of cardiological drug considering bones are analysed. Additionally possible advantages of selected drugs used for cardiovascular diseases on osteoporosis prevention are evaluated. Drugs used for osteoporosis treatment may heave adverse effects on cardiovascular system. The article has detailed analyses of current drug classes, such as the bisphosphonates, strontium ranelate as well as a review of the controversy surrounding hormone replacement therapy (HRT) and the selective oestrogen receptor modulators (SERMs). Lastly discussion of adverse effects on the heart of calcium and drugs influencing calcium metabolism such as vitamin D, parathormone and calcitonin is performed.

摘要

绝经后最常见的医学病症是骨质疏松症和动脉粥样硬化疾病。传统上,这两种病症被认为没有关联,它们的共存被归因于完全与年龄相关的独立过程。心血管疾病与骨质疏松症之间可能存在的联系促使如今不仅要分析可能存在关联的证据,还要确定用于这两种疾病的药物的相互有益和不利影响。这就是为什么要关注骨质疏松症治疗与用于动脉粥样硬化的药物之间的相互干扰。此外,还要分析考虑到骨骼的心脏病药物的副作用。此外,还要评估用于心血管疾病的某些药物在预防骨质疏松症方面可能具有的优势。用于治疗骨质疏松症的药物可能会对心血管系统产生不利影响。本文详细分析了当前的药物类别,如双膦酸盐、雷奈酸锶,以及围绕激素替代疗法(HRT)和选择性雌激素受体调节剂(SERMs)的争议综述。最后,讨论了钙以及影响钙代谢的药物(如维生素D、甲状旁腺激素和降钙素)对心脏的不利影响。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验