Roust Lori R, DiBaise John K
aDivisions of Endocrinology bGastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona, USA.
Curr Opin Clin Nutr Metab Care. 2017 Mar;20(2):138-144. doi: 10.1097/MCO.0000000000000352.
The purpose of this review is to provide an update of recent additions to our understanding of the prevalence of nutrient deficiencies and the potential role of preoperative weight loss in contributing to these deficiencies in obese individuals planning to undergo bariatric surgery.
Recent reports that have included bariatric surgery candidates from sites around the world have shown consistent deficiencies in a variety of nutrients. Although protein-energy malnutrition is uncommon preoperatively, micronutrient deficiencies occur commonly with multiple deficiencies often present in the same individual. No difference in the prevalence of deficiency between men and women is apparent, and a standard profile of susceptibility to deficiency has not been identified. In the only studies that have evaluated dietary intake of total energy, macronutrients and micronutrients preoperatively, despite an excess of calories ingested, micronutrient intake tends to be lower than recommended.
A high prevalence of micronutrient deficiencies, especially vitamin D, folate, B12 and iron, is present in obese individuals being considered for bariatric surgery. Despite high-caloric intake, the deficiencies present appear to be related to the poor quality of the diet and low micronutrient intake. These findings strengthen prior recommendations of routine preoperative nutritional screening. Because a standard profile of susceptibility to deficiency has not been identified, extensive nutritional screening, including micronutrient testing, should be considered in all patients in the preoperative setting. Finally, we recommend early supplementation of vitamins and minerals based on laboratory assessment and incorporation of a program to optimize eating behaviors prior to surgery.
本综述旨在更新我们对营养缺乏症患病率的最新认识,以及术前体重减轻在导致计划接受减肥手术的肥胖个体出现这些缺乏症方面的潜在作用。
最近来自世界各地涉及减肥手术候选者的报告显示,多种营养素存在持续缺乏的情况。虽然术前蛋白质能量营养不良并不常见,但微量营养素缺乏症很常见,且同一个体往往存在多种缺乏症。男性和女性之间缺乏症的患病率没有明显差异,也尚未确定易患缺乏症的标准特征。在唯一评估术前总能量、宏量营养素和微量营养素饮食摄入量的研究中,尽管摄入的热量过多,但微量营养素摄入量往往低于推荐量。
考虑接受减肥手术的肥胖个体中,微量营养素缺乏症的患病率很高,尤其是维生素D、叶酸、维生素B12和铁。尽管热量摄入高,但目前的缺乏症似乎与饮食质量差和微量营养素摄入量低有关。这些发现强化了术前常规营养筛查的先前建议。由于尚未确定易患缺乏症的标准特征,术前应考虑对所有患者进行广泛的营养筛查,包括微量营养素检测。最后,我们建议根据实验室评估尽早补充维生素和矿物质,并在手术前纳入优化饮食行为的计划。