Division of Surgical Critical Care, Department of Surgery, Stroger Hospital of Cook County, Chicago, Illinois, USA.
Curr Opin Clin Nutr Metab Care. 2011 Nov;14(6):635-41. doi: 10.1097/MCO.0b013e32834b3355.
Obesity is a growing worldwide epidemic. Obese patients are often deficient in micronutrients despite macronutrient excess. Bariatric surgery is an increasingly utilized modality in the treatment of obesity and obesity-related conditions. Bariatric surgery itself may cause or exacerbate micronutrient deficiencies with serious sequelae. This review will focus on perioperative strategies to detect, prevent and treat micronutrient deficiencies in patients undergoing bariatric surgery, and will highlight practical and clinical aspects of these nutritional problems.
Micronutrient deficiency is common in obese patients undergoing bariatric surgery both preoperatively and postoperatively. Bariatric procedures with a malabsorptive component are more likely to result in postoperative micronutrient deficiency. A system-based approach will facilitate clinical suspicion of specific or combined micronutrient deficiencies, leading to appropriate laboratory tests for confirmation. Supplementation by the oral route is always tried first, reserving parenteral administration for specific situations.
Clinicians should be aware that micronutrient deficiencies are common in obese patients who may have macronutrient excess. Micronutrient deficiency may exist preoperatively or be caused by bariatric procedures themselves. A systematic and team-based approach will decrease morbidity associated with delays in diagnosis and treatment.
肥胖是一种在全球范围内日益流行的疾病。尽管摄入了大量的宏量营养素,肥胖患者仍经常缺乏微量营养素。减重手术是治疗肥胖和肥胖相关疾病的一种越来越常用的方法。减重手术本身可能导致或加剧微量营养素缺乏,从而产生严重的后果。本综述将重点介绍在接受减重手术的患者中检测、预防和治疗微量营养素缺乏的围手术期策略,并强调这些营养问题的实际和临床方面。
肥胖患者在接受减重手术前后都普遍存在微量营养素缺乏。具有吸收不良成分的减重手术更有可能导致术后微量营养素缺乏。基于系统的方法将有助于临床怀疑特定或联合的微量营养素缺乏,并进行相应的实验室检查以确认。首先尝试通过口服途径补充,仅在特定情况下保留肠外给药。
临床医生应意识到,肥胖患者可能存在微量营养素过剩的情况,而微量营养素缺乏在术前或由减重手术本身引起。系统的、团队合作的方法将降低因诊断和治疗延误而导致的发病率。