Teoh Laurence S G, Eyles Jillian P, Makovey Joanna, Williams Matthew, Kwoh C Kent, Hunter David J
Royal North Shore Hospital and Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia.
Department of Medicine, University of Arizona Arthritis Center and Division of Rheumatology, University of Arizona College of Medicine, Tucson, Arizona, USA.
Int J Rheum Dis. 2017 Oct;20(10):1383-1392. doi: 10.1111/1756-185X.12950. Epub 2016 Dec 12.
To determine the impact of an osteoarthritis-specific multidisciplinary conservative care program (OACCP) on willingness for surgery (WFS) and to identify changes and factors in our cohort that influence and predict willingness for surgery.
Consecutive OACCP participants with hip or knee OA, with WFS (willing, unsure or unwilling) data for at least two appointments were included. The proportions of unwilling versus willing/unsure patients at baseline and last appointment were compared using McNemar's test. Logistic regression was used to analyze baseline age, gender, main language, educational status, living situation, number of comorbidities, index joint, non-index joint osteoarthritis, completion of program, baseline and change in pain, function, depression, body mass index and 6-min walk test (6MWT) for association with changing WFS.
At baseline 203/409 were unwilling for surgery while by final appointment 234/409 were unwilling (P = 0.002). Of the 206 initially willing/unsure participants, 63/206 (30.6%) became unwilling by final appointment. Index joint, completion of program, baseline and change in pain, self-reported function and 6MWT were independently associated with becoming unwilling. Final model from multivariate logistic regression analysis regarding becoming unwilling included baseline pain (P < 0.001), change in pain (P < 0.001), completion of program (P < 0.001) and age (P = 0.004).
A conservative OA-specific treatment program that improves pain and function can reduce willingness for surgery among participants with hip or knee OA. The strongest determinants of this reduction in willingness were baseline and change in pain, completion of the program and participant age.
确定骨关节炎特异性多学科保守治疗方案(OACCP)对手术意愿(WFS)的影响,并识别我们队列中影响和预测手术意愿的变化及因素。
纳入连续参与OACCP的髋或膝骨关节炎患者,这些患者至少有两次预约时的WFS(愿意、不确定或不愿意)数据。使用McNemar检验比较基线和最后一次预约时不愿意与愿意/不确定患者的比例。采用逻辑回归分析基线年龄、性别、主要语言、教育状况、生活状况、合并症数量、指数关节、非指数关节骨关节炎、方案完成情况、基线及疼痛、功能、抑郁、体重指数和6分钟步行试验(6MWT)的变化与WFS变化的相关性。
基线时203/409例患者不愿意接受手术,而到最后一次预约时,234/409例患者不愿意接受手术(P = 0.002)。在最初愿意/不确定的206例参与者中,63/206(30.6%)到最后一次预约时变得不愿意接受手术。指数关节、方案完成情况、基线及疼痛、自我报告的功能和6MWT的变化与变得不愿意接受手术独立相关。多变量逻辑回归分析关于变得不愿意接受手术的最终模型包括基线疼痛(P < 0.001)、疼痛变化(P < 0.001)、方案完成情况(P < 0.001)和年龄(P = 0.004)。
一个能改善疼痛和功能的保守性骨关节炎特异性治疗方案可降低髋或膝骨关节炎参与者的手术意愿。这种意愿降低的最主要决定因素是基线及疼痛变化、方案完成情况和参与者年龄。