Bernbaum J C, Sasanow S R, Churella H R, Daft A
Neonatal Follow-Up Program, Children's Hospital of Philadelphia, PA 19104.
J Pediatr. 1989 Oct;115(4):652-6. doi: 10.1016/s0022-3476(89)80303-8.
We conducted a double-blind, randomized study to test the hypothesis that a whey-dominant formula permits a growth and metabolic advantage over a casein-dominant formula in preterm infants after hospital discharge. Nineteen low birth weight infants were studied for 6 months from the time of discharge. Ten received a casein-dominant formula, and nine received a whey-dominant formula. Growth (weight, length, head circumference, mid-arm circumference, and skin-fold thickness), biochemical measurements (alkaline phosphatase activity, acid-base status, and hemoglobin, serum total protein, albumin, and urea nitrogen levels), and quantity of formula intake did not differ significantly between the groups over a 6-month study period. Serum transthyretin and urea nitrogen concentrations differed significantly between the two feeding groups at the day of entry into the study only. The results indicate that, after hospital discharge, premature infants fed a whey-dominant formula do not differ in growth or biochemical measurements from those fed a casein-dominant formula.
我们进行了一项双盲随机研究，以检验以下假设：出院后，以乳清蛋白为主的配方奶粉相比以酪蛋白为主的配方奶粉，能使早产儿获得生长和代谢方面的优势。19名低体重婴儿自出院起接受了6个月的研究。10名婴儿接受以酪蛋白为主的配方奶粉，9名婴儿接受以乳清蛋白为主的配方奶粉。在6个月的研究期内，两组婴儿的生长指标（体重、身长、头围、上臂围和皮褶厚度）、生化指标（碱性磷酸酶活性、酸碱状态以及血红蛋白、血清总蛋白、白蛋白和尿素氮水平）和配方奶粉摄入量均无显著差异。仅在研究开始当天，两组喂养方式的血清转甲状腺素蛋白和尿素氮浓度存在显著差异。结果表明，出院后，食用以乳清蛋白为主配方奶粉的早产儿与食用以酪蛋白为主配方奶粉的早产儿在生长或生化指标上并无差异。
