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类癌综合征表现的肝细胞癌患者生存期相对较长。

Relatively Long Survival in Hepatocellular Carcinoma Presenting With Carcinoid Syndrome.

作者信息

Nwokediuko Sylvester Chuks, Uchenna Ijoma, Esther Ofoegbu, Okechukwu Okafor, Augustine Onuh, Charity Ajuyah

机构信息

Departments of Medicine, University of Nigeria Teaching Hospital Ituku/Ozall, Enugu, Nigeria.

Departments of Morbid Anatomy, University of Nigeria Teaching Hospital Ituku/Ozall, Enugu, Nigeria.

出版信息

Gastroenterology Res. 2010 Feb;3(1):46-49. doi: 10.4021/gr2010.02.171w. Epub 2010 Jan 20.

Abstract

Hepatocelluar carcinoma is one of the commonest cancers in Nigeria. Some patients may manifest a variety of paraneoplastic syndromes. Carcinoid syndrome is an extremely rare presentation of hepatocellular carcinoma. A 57-year old man presented with recurrent facial flushing and diarrhea, tricuspid regurgitation, and very high level of urinary hydroxyindoleacetic acid (HIAA) as the first manifestation of a multicentric hepatic lesion which proved histologically to be hepatocellular carcinoma. The lesions also exhibited arterial hypervascularization on contrast enhanced computerized tomography. The patient is still alive after 6 years of symptoms.

摘要

肝细胞癌是尼日利亚最常见的癌症之一。一些患者可能会出现各种副肿瘤综合征。类癌综合征是肝细胞癌极为罕见的表现形式。一名57岁男性以反复面部潮红、腹泻、三尖瓣反流以及尿中高香草酸(HIAA)水平极高为首发症状,这些症状是多中心肝脏病变的表现,经组织学证实为肝细胞癌。在增强计算机断层扫描中,这些病变还表现出动脉期血管强化。该患者出现症状6年后仍然存活。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4579/5139840/b3f11976bd0b/gr-03-046-g001.jpg

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