血管性认知障碍分类共识研究。
The Vascular Impairment of Cognition Classification Consensus Study.
机构信息
Dementia Research Group, Faculty of Health Sciences, School of Clinical Sciences, University of Bristol, Southmead Hospital, Bristol, UK.
Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, UK.
出版信息
Alzheimers Dement. 2017 Jun;13(6):624-633. doi: 10.1016/j.jalz.2016.10.007. Epub 2016 Dec 10.
INTRODUCTION
Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment.
METHODS
The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines.
RESULTS
VICCCS had a mean of 122 (98-153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge.
DISCUSSION
VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research.
简介
许多诊断标准试图解决血管性认知障碍（VCI）临床表现的变异性和诊断难题，但没有一个标准被普遍接受。这些标准不容易进行比较，影响了临床诊断率，进而影响了患病率估计、研究和治疗。
方法
血管认知障碍分类共识研究（VICCCS）涉及来自 27 个国家的 27 名参与者（98%为学术研究人员），他们通过在线德尔菲共识研究进行了评估。参与者对之前提出的概念进行了回顾，以制定新的指南。
结果
VICCCS 在整个研究中平均有 122 名（98-153 名）参与者，67%的参与者代表了共识。VICCCS 重新定义了 VCI，包括轻度和重度 VCI 以及亚型的分类。它提出了新的标准化 VCI 相关术语和未来的研究重点，以解决当前知识空白。
讨论
VICCCS 提出了一个基于共识的 VCI 更新概念，旨在促进研究的标准化。
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