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创伤后应激障碍和抑郁症移民的躯体共病——一项前瞻性队列研究。

Somatic comorbidity among migrants with posttraumatic stress disorder and depression - a prospective cohort study.

作者信息

Lolk Mette, Byberg Stine, Carlsson Jessica, Norredam Marie

机构信息

Danish Research Centre for Migration, Ethnicity and Health, Section of Health Services Research, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5A, Copenhagen, Denmark.

Competence Centre for Transcultural Psychiatry, Mental Health Centre Ballerup, Mental Health Services of the Capital Region of Denmark, Maglevaenget 2, 2750, Ballerup, Denmark.

出版信息

BMC Psychiatry. 2016 Dec 13;16(1):447. doi: 10.1186/s12888-016-1149-2.

Abstract

BACKGROUND

In a cohort of migrants in Denmark, we compared somatic disease incidence among migrants diagnosed with posttraumatic stress disorder (PTSD) and depression with migrants without a diagnosed psychiatric disorder.

METHODS

The study builds on a unique cohort of migrants who obtained residence permit in Denmark from 1993 to 2010 (N = 92,104). The association with somatic disease was explored via register linkage. We used Poisson regression to model incidence rate ratios (IRR) adjusted for age, sex, income and region of origin. The Danish Data Protection Agency granted authorisation for the implementation of the project (No 2012-41-0065).

RESULTS

Our results showed that migrants diagnosed with PTSD and depression had significantly higher rates of somatic diseases compared with migrants without diagnosed psychiatric disorders - especially, infectious disease (IRR, 1.89; 95% CI, 1.45-2.48; p < 0.01), neurological disease (IRR, 2.35; 95% CI, 1.91-2.91; p < 0.01) and pulmonary disease (IRR, 1.69; 95% CI, 1.37-2.00; p < 0.01). We further saw differences in the IRRs according to region of origin.

CONCLUSION

Migrants with PTSD and depression had a significantly higher rates of somatic comorbidity compared with migrants without a diagnosed psychiatric disorder. The rates were especially high for infectious, neurological and pulmonary diseases. Our results further suggest difference in the rates of somatic comorbidity according to region of. Preventive and treatment services should pay special attention to improve the overall health of migrants with PTSD and depression.

摘要

背景

在丹麦的一组移民中,我们比较了被诊断患有创伤后应激障碍(PTSD)和抑郁症的移民与未被诊断患有精神疾病的移民的躯体疾病发病率。

方法

该研究基于1993年至2010年在丹麦获得居住许可的一组独特移民队列(N = 92,104)。通过登记联动探索与躯体疾病的关联。我们使用泊松回归模型来模拟调整年龄、性别、收入和原籍地区后的发病率比(IRR)。丹麦数据保护局批准了该项目的实施(编号2012 - 41 - 0065)。

结果

我们的结果表明,与未被诊断患有精神疾病的移民相比,被诊断患有PTSD和抑郁症的移民的躯体疾病发病率显著更高——尤其是传染病(IRR,1.89;95%CI,1.45 - 2.48;p < 0.01)、神经系统疾病(IRR,2.35;95%CI,1.91 - 2.91;p < 0.01)和肺部疾病(IRR,1.69;95%CI,1.37 - 2.00;p < 0.01)。我们还发现根据原籍地区,IRR存在差异。

结论

与未被诊断患有精神疾病的移民相比,患有PTSD和抑郁症的移民的躯体合并症发病率显著更高。传染病、神经系统疾病和肺部疾病的发病率尤其高。我们的结果进一步表明,根据地区不同,躯体合并症的发病率存在差异。预防和治疗服务应特别关注改善患有PTSD和抑郁症的移民的整体健康状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03eb/5153678/e6db05364117/12888_2016_1149_Fig1_HTML.jpg

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