Hayes D K, Stambaugh K I
Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, TX 78234-6200.
Laryngoscope. 1989 Oct;99(10 Pt 1):1016-9. doi: 10.1288/00005537-198210000-00008.
This study was undertaken to determine whether the application of a standardized chemical peel with an occlusive tape dressing to an acutely raised skin flap (as in combining rhytidectomy with chemical peel) affects skin flap viability. Thirty-six 4-cm x 4-cm dorsal skin flaps were raised on guinea pigs and sutured back into place. Eighteen of these flaps were simultaneously treated with a single application of Baker's solution and a 24-hour occlusive tape dressing. A mean of 3.1 cm2 of the nonpeeled flaps necrosed, compared with 6.3 cm2 of the peeled flaps, a statistically significant increase in tissue loss in flaps that were simultaneously chemically peeled. We conclude that application of Baker's solution with an occlusive tape dressing to an acutely raised skin flap impairs skin flap viability and may result in skin flap necrosis.
本研究旨在确定在急性抬高的皮瓣(如在除皱术联合化学剥脱术中)应用标准化化学剥脱并使用封闭胶带敷料是否会影响皮瓣的存活能力。在豚鼠身上掀起36个4厘米×4厘米的背部皮瓣,然后缝合回原位。其中18个皮瓣同时接受单次贝克溶液治疗和24小时封闭胶带敷料处理。未进行化学剥脱的皮瓣平均坏死面积为3.1平方厘米,而进行化学剥脱的皮瓣坏死面积为6.3平方厘米,在同时进行化学剥脱的皮瓣中组织损失有统计学意义的增加。我们得出结论,对急性抬高的皮瓣应用贝克溶液并使用封闭胶带敷料会损害皮瓣的存活能力,并可能导致皮瓣坏死。