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[在严重外源性缺氧(8%氧气)条件下的胃癌放射治疗]

[Radiotherapy of stomach cancer under conditions of severe exogenous hypoxia (8% O2)].

作者信息

Khvorostenko M I

出版信息

Med Radiol (Mosk). 1989 Sep;34(9):32-7.

PMID:2796641
Abstract

Irradiation of 116 stomach cancer patients was performed under the conditions of hypoxia caused by the inhalation of a gaseous mixture containing (8 +/- 0.5%) O2; irradiation of 108 patients was performed in the air. The method of hypoxic radiotherapy of stomach cancer is described. The authors present some data on radiation reactions, tumor regression, the condition of tumorous and normal tissue after radiotherapy under the conditions of hypoxia which permitted an increase in a tumor radiation dose and a decrease in the number and gravity of radiation reactions. The above method of large field preoperative irradiation made it possible to improve short-term results of combined therapy of stomach cancer patients.

摘要

对116例胃癌患者在吸入含(8±0.5%)氧气的气体混合物导致的缺氧条件下进行了照射;对108例患者在空气中进行了照射。描述了胃癌的低氧放射治疗方法。作者给出了一些关于放射反应、肿瘤消退、放疗后肿瘤组织和正常组织状况的数据,在低氧条件下放疗可增加肿瘤放射剂量并减少放射反应的数量和严重程度。上述大野术前照射方法使改善胃癌患者综合治疗的短期效果成为可能。

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