免疫毒素对人胶质瘤细胞的作用。
The effect of immunotoxin against human glioma cells.
作者信息
Manome Y, Watanabe M, Ohno T
机构信息
Department of Neurosurgery, Jikei University School of Medicine, Tokyo, Japan.
出版信息
Neurochirurgia (Stuttg). 1989 Sep;32(5):146-9. doi: 10.1055/s-2008-1054024.
PMID:2797358
Abstract
The authors produced immunotoxin by coupling the diphtheria toxin fragment A to the monoclonal antibody against a human glioma cell line. This toxin selectively inhibited protein synthesis of glioma cells in culture.
摘要
作者通过将白喉毒素A片段与抗人类胶质瘤细胞系的单克隆抗体偶联来制备免疫毒素。这种毒素在培养中选择性地抑制胶质瘤细胞的蛋白质合成。
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