Hachache T, Meftahi H, Foret M, Kuentz F, Milongo R, Christollet M, Cordonnier D J, Arnaud J, Favier A
AGDUC, CHUR Grenoble, La Tronche.
Nephrologie. 1989;10(2):87-90.
In patients with chronic renal insufficiency undergoing hemodialysis, the seric zinc level was significantly lower than in normal subjects. In 7 patients this was even more marked prior to their first hemodialysis session. Following hemodialysis this level increased, but by comparing the zinc level to that of the binding proteins it could be seen that this result was a reflection of the hemo-concentration phenomenon. During hemodialysis there was no change in the zinc level of dialysate. Finally, a significant increase in the seric level of the 7 new patients was noted after 6 months of hemodialysis treatment. This increase reached the mean level observed in the 26 other patients who had been undergoing hemodialysis from between 8 and 87 months, but pre-dialysis normalization of seric zinc levels was not attained. The reasons for this increase in the 7 recently hemodialysed patients receiving no zinc treatment are discussed.
在接受血液透析的慢性肾功能不全患者中，血清锌水平显著低于正常受试者。在7名患者中，首次血液透析前这一情况更为明显。血液透析后该水平有所升高，但通过将锌水平与结合蛋白的水平进行比较可以看出，这一结果是血液浓缩现象的反映。血液透析过程中透析液中的锌水平没有变化。最后，在7名新患者接受6个月血液透析治疗后，其血清水平显著升高。这一升高达到了在接受8至87个月血液透析的其他26名患者中观察到的平均水平，但血清锌水平在透析前未恢复正常。文中讨论了7名近期接受血液透析且未接受锌治疗的患者血清锌水平升高的原因。
