J Laryngol Otol. 2017 Feb;131(2):96-105. doi: 10.1017/S0022215116009749. Epub 2016 Dec 15.
To verify the prevalence of cervical lymph node metastasis in adenoid cystic carcinoma of major salivary glands, and to establish recommendations for elective neck treatment.
A search was conducted of the US National Library of Medicine database. Appropriate articles were selected from the abstracts, and the original publications were obtained to extract data.
Among 483 cases of major salivary gland adenoid cystic carcinoma, a total of 90 (18.6 per cent) had cervical metastasis. The prevalence of positive nodes from adenoid cystic carcinoma was 14.5 per cent for parotid gland, 22.5 per cent for submandibular gland and 24.7 per cent for sublingual gland. Cervical lymph node metastasis occurred more frequently in patients with primary tumour stage T3-4 adenoid cystic carcinoma, and was usually located in levels II and III in the neck.
Adenoid cystic carcinoma of the major salivary glands is associated with a significant prevalence of cervical node metastasis, and elective neck treatment is indicated for T3 and T4 primary tumours, as well as tumours with other histological risk factors.
验证大唾液腺腺样囊性癌颈淋巴结转移的发生率，并制定选择性颈部治疗的建议。
检索美国国立医学图书馆数据库。从摘要中筛选合适的文章，并获取原始出版物以提取数据。
在483例大唾液腺腺样囊性癌病例中，共有90例（18.6%）发生颈转移。腺样囊性癌阳性淋巴结的发生率在腮腺为14.5%，下颌下腺为22.5%，舌下腺为24.7%。颈淋巴结转移在原发肿瘤为T3 - 4期的腺样囊性癌患者中更常见，且通常位于颈部Ⅱ区和Ⅲ区。
大唾液腺腺样囊性癌与颈淋巴结转移的显著发生率相关，对于T3和T4期原发肿瘤以及具有其他组织学危险因素的肿瘤，建议进行选择性颈部治疗。
