Faculty of Medicine, Department of Radiology, Hacettepe University, Ankara, Turkey.
Faculty of Medicine, Department of Neurology, Hacettepe University, Ankara, Turkey.
J Neurointerv Surg. 2017 Dec;9(12):1214-1218. doi: 10.1136/neurintsurg-2016-012760. Epub 2016 Dec 14.
To report our initial experience with the Catch Plus thrombectomy device (CPD) in patients with acute ischemic stroke (AIS).
We retrospectively evaluated the procedural variables as well as the clinical and angiographic outcomes of patients with acute occlusion of a major intracranial artery in the anterior circulation who were treated with CPD at our center. Baseline characteristics (gender, age, comorbidities, cardiovascular risk factors, National Institutes of Health Stroke Scale (NIHSS) score, and vessel occlusion sites) of these patients were recorded. Thrombolysis in Cerebral Infarction (TICI) score, incidence of symptomatic and asymptomatic bleeding, and 90 day modified Rankin Scale (mRS) scores were evaluated as indicators of outcome.
38 patients with a mean age of 67.5 years were treated with CPD. Mean time from symptom onset to procedure initiation was 226.7 min. Recanalization (TICI 2b-3) was achieved in 27 patients (71.1%). The median NIHSS score on admission was 20. Rates of symptomatic and asymptomatic intracerebral hemorrhage were 7.9% and 13.2%, respectively. The 90 day clinical follow-up data were available for 37 patients. The 90 day mortality rate was 18.9%, and the 90 day clinically acceptable functional outcome (mRS score ≤2) rate was 43.2% (mRS score 0-3, 54.1%). Very distal thrombectomy involving the cortical arteries was performed on four patients without complications.
Our initial experience suggests that mechanical thrombectomy with the CPD improves 90 day outcomes of patients with AIS by facilitating effective recanalization.
报告我们在急性缺血性脑卒中(AIS)患者中使用 Catch Plus 血栓切除术装置(CPD)的初步经验。
我们回顾性评估了在我们中心接受 CPD 治疗的前循环大血管急性闭塞的急性脑梗死患者的手术变量以及临床和血管造影结果。记录了这些患者的基线特征(性别、年龄、合并症、心血管危险因素、国立卫生研究院卒中量表(NIHSS)评分和血管闭塞部位)。溶栓治疗脑梗死(TICI)评分、症状性和无症状性出血的发生率以及 90 天改良 Rankin 量表(mRS)评分作为转归的指标进行评估。
38 例平均年龄为 67.5 岁的患者接受了 CPD 治疗。从症状发作到开始手术的平均时间为 226.7 分钟。27 例患者(71.1%)达到再通(TICI 2b-3)。入院时的 NIHSS 评分中位数为 20。症状性和无症状性颅内出血的发生率分别为 7.9%和 13.2%。37 例患者可获得 90 天临床随访数据。90 天死亡率为 18.9%,90 天临床可接受的功能结局(mRS 评分≤2)率为 43.2%(mRS 评分 0-3,54.1%)。4 例患者行非常远端皮质动脉血栓切除术,无并发症发生。
我们的初步经验表明,CPD 的机械血栓切除术通过促进有效的再通改善了 AIS 患者的 90 天转归。