Amsterdam Brain and Cognition Centre, University of Amsterdam, Nieuwe Achtergracht 129B, 1018 WT Amsterdam, The Netherlands; and at the Netherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA Amsterdam, The Netherlands.
Psychological Methods Department, University of Amsterdam, Nieuwe Achtergracht 129B, 1018 WT Amsterdam, The Netherlands.
Nat Rev Neurosci. 2016 Dec 15;18(1):57-65. doi: 10.1038/nrn.2016.163.
The human subcortex is a densely populated part of the brain, of which only 7% of the individual structures are depicted in standard MRI atlases. In vivo MRI of the subcortex is challenging owing to its anatomical complexity and its deep location in the brain. The technical advances that are needed to reliably uncover this 'terra incognita' call for an interdisciplinary human neuroanatomical approach. We discuss the emerging methods that could be used in such an approach and the incorporation of the data that are generated from these methods into model-based cognitive neuroscience frameworks.
人类皮质下区是大脑中一个密集的区域，其个体结构中只有 7%在标准 MRI 图谱中有所描绘。由于其解剖结构的复杂性及其在大脑中的深层位置，皮质下区的活体 MRI 检查颇具挑战性。为了可靠地揭示这片“未知领域”，需要采用跨学科的人类神经解剖学方法。我们讨论了此类方法中可能使用的新兴方法，以及将这些方法生成的数据纳入基于模型的认知神经科学框架中。
