Bystrzonowski Nicola, Hachach-Haram Nadine, Kanapathy Muholan, Richards Toby, Mosahebi Afshin
Royal Free Hospital Wound Healing Group, Department of Plastic and Reconstructive Surgery, Royal Free London Hospital, London, United Kingdom; and Royal Free Hospital Wound Healing Group, Department of Plastic and Reconstructive Surgery, Royal Free Hospital, London, United Kingdom.
Plast Reconstr Surg Glob Open. 2016 Nov 21;4(11):e1119. doi: 10.1097/GOX.0000000000001119. eCollection 2016 Nov.
Wound care represents a significant socioeconomic burden, with over half of chronic wounds taking up to a year to heal. Measures to accelerate wound healing are beneficial to patients and also reduce the cost and burden of wound management. Epidermal grafting (EG) is an emerging option for autologous skin grafting in the outpatient setting to improve wound healing. Although several case series have previously reported good clinical outcome with EG, the healing rate in comparison to conservative wound management is not known. In this report, we compare the weekly healing rate of 2 separate wounds in the same patient, one treated with EG and the other with dressings. The treated wound showed accelerated healing, with the healing rate being the highest at the first 2 weeks after EG. The average healing time of the treated wound was 40% faster compared with the control wound. EG accelerates healing of acute wounds, potentially reducing the healthcare cost and surgical burden.
伤口护理带来了巨大的社会经济负担,超过半数的慢性伤口需要长达一年的时间才能愈合。加速伤口愈合的措施对患者有益,同时也能降低伤口管理的成本和负担。表皮移植(EG)是门诊自体皮肤移植的一种新兴选择,用于改善伤口愈合。尽管此前有多个病例系列报道EG具有良好的临床效果,但与保守伤口管理相比,其愈合率尚不清楚。在本报告中,我们比较了同一患者两个不同伤口的每周愈合率,一个伤口接受EG治疗,另一个伤口使用敷料治疗。接受治疗的伤口愈合加速,在EG治疗后的前两周愈合率最高。与对照伤口相比,治疗伤口的平均愈合时间快40%。EG可加速急性伤口的愈合,有可能降低医疗成本和手术负担。