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Innate Immune Responses by Respiratory Viruses, Including Rhinovirus, During Asthma Exacerbation.呼吸道病毒（包括鼻病毒）在哮喘加重期间的先天免疫反应。
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Immunoglobulin E-Dependent Activation of Immune Cells in Rhinovirus-Induced Asthma Exacerbation.鼻病毒诱导的哮喘加重中免疫球蛋白E依赖的免疫细胞激活
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本文引用的文献

1
Rhinovirus and serum IgE are associated with acute asthma exacerbation severity in children.鼻病毒和血清免疫球蛋白E与儿童急性哮喘加重的严重程度相关。
J Allergy Clin Immunol. 2016 Nov;138(5):1467-1471.e9. doi: 10.1016/j.jaci.2016.04.044. Epub 2016 Jun 15.
2
Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations.使用奥马珠单抗或吸入性糖皮质激素强化进行季节性前治疗，以预防秋季哮喘发作。
J Allergy Clin Immunol. 2015 Dec;136(6):1476-1485. doi: 10.1016/j.jaci.2015.09.008. Epub 2015 Oct 27.
3
Revision of omalizumab dosing table for dosing every 4 instead of 2 weeks for specific ranges of bodyweight and baseline IgE.针对特定体重范围和基线IgE水平，将奥马珠单抗给药间隔从每2周调整为每4周的给药剂量表修订版。
Regul Toxicol Pharmacol. 2015 Feb;71(1):68-77. doi: 10.1016/j.yrtph.2014.12.002. Epub 2014 Dec 8.
4
Development and validation of the Composite Asthma Severity Index--an outcome measure for use in children and adolescents.《复合哮喘严重程度指数的制定与验证——一种适用于儿童和青少年的结局指标》。
J Allergy Clin Immunol. 2012 Mar;129(3):694-701. doi: 10.1016/j.jaci.2011.12.962. Epub 2012 Jan 12.
5
Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children.奥马珠单抗（抗 IgE）治疗城市内儿童哮喘的随机试验。
N Engl J Med. 2011 Mar 17;364(11):1005-15. doi: 10.1056/NEJMoa1009705.
6
Predictors of symptoms are different from predictors of severe exacerbations from asthma in children.儿童哮喘症状的预测因素与严重恶化的预测因素不同。
Chest. 2011 Jul;140(1):100-107. doi: 10.1378/chest.10-2794. Epub 2011 Feb 3.
7
Assessing the validity of self-reported medication adherence among inner-city asthmatic adults: the Medication Adherence Report Scale for Asthma.评估市中心哮喘成年患者自我报告的药物依从性的有效性：哮喘药物依从性报告量表
Ann Allergy Asthma Immunol. 2009 Oct;103(4):325-31. doi: 10.1016/s1081-1206(10)60532-7.
8
Severe exacerbations in children with mild asthma: characterizing a pediatric phenotype.轻度哮喘患儿的严重发作：儿科表型特征分析
J Asthma. 2008 Aug;45(6):513-7. doi: 10.1080/02770900802017751.
9
Pediatric asthma admissions: chronic severity and acute exacerbations.小儿哮喘住院情况：慢性严重程度与急性加重
J Asthma. 2007 May;44(4):285-9. doi: 10.1080/02770900701340445.
10
An international observational prospective study to determine the cost of asthma exacerbations (COAX).一项旨在确定哮喘急性加重成本的国际观察性前瞻性研究（COAX研究）。
Respir Med. 2006 Mar;100(3):434-50. doi: 10.1016/j.rmed.2005.06.012. Epub 2005 Aug 11.

Omalizumab Is Associated with Reduced Acute Severity of Rhinovirus-triggered Asthma Exacerbation.

作者信息

Kantor David B, McDonald Molly C, Stenquist Nicole, Schultz Blake J, Smallwood Craig D, Nelson Kyle A, Phipatanakul Wanda, Hirschhorn Joel N

机构信息

1 Boston Children's Hospital Boston, Massachusetts.

2 Harvard Medical School Boston, Massachusetts and.

出版信息

Am J Respir Crit Care Med. 2016 Dec 15;194(12):1552-1555. doi: 10.1164/rccm.201606-1145LE.

DOI:10.1164/rccm.201606-1145LE
PMID:27976938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5215034/
Abstract
摘要