Centre of Genomics and Policy, McGill University, Montreal, Quebec, Canada.
School for the Future of Innovation in Society, Arizona State University, and Consortium for Science, Policy &Outcomes, Tempe, Arizona, USA.
Genet Med. 2017 Jul;19(7):838-841. doi: 10.1038/gim.2016.189. Epub 2016 Dec 15.
Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing.Genet Med advance online publication 15 December 2016.
公共变异数据库支持基因组数据的管理、临床解读和共享，从而减少诊断中的有害错误或延迟。随着变异数据库在临床环境中的应用越来越多，人们担心疏忽的变异解读会伤害患者并引发责任问题。本文探讨了实验室、公共变异数据库和临床基因组学医师不断演变的法律责任，并为数据库推荐了一个治理框架，以促进负责任的数据共享。《基因医学》在线发表于 2016 年 12 月 15 日。
