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负压伤口治疗辅助剖宫产术后因严重细菌性蜂窝织炎伴腹部脓肿进行手术清创后的恢复:一例符合 CARE 标准的病例报告

Negative pressure wound therapy aids recovery following surgical debridement due to severe bacterial cellulitis with abdominal abscess post-cesarean: A case report (CARE-Compliant).

作者信息

Young Christopher N J, Ng Ka Ying Bonnie, Webb Vanessa, Vidow Sarah, Parasuraman Rajeswari, Umranikar Sameer

机构信息

Department of Molecular Medicine, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK. Department of Obstetrics and Gynaecology, Princess Anne Hospital, Southampton, UK.

出版信息

Medicine (Baltimore). 2016 Dec;95(50):e5397. doi: 10.1097/MD.0000000000005397.

Abstract

INTRODUCTION

Bacterial cellulitis post-Cesarean section is rare. Negative pressure wound therapy (NPWT) is widely used in various medical specialities; its effectiveness in obstetrics however remains the topic of debate-used predominantly as an adjunct to secondary intention specific to high-risk patient groups. Its application in the treatment of actively infected wounds post-Cesarean is not well documented. Here, we document NPWT in the treatment of an unusually severe case of bacterial cellulitis with abdominal abscess postpartum. We provide a unique photographic timeline of wound progression following major surgical debridement, documenting the effectiveness of 2 different NPWT systems (RENASYS GO and PICO, Smith & Nephew). We report problems encountered using these NPWT systems and "ad-hoc" solutions to improve efficacy and patient experience.A 34-year-old primiparous Caucasian female with no prior history or risk factors for infection and a normal body mass index (BMI) presented with severe abdominal pain, swelling, and extensive abdominal redness 7 days postemergency Cesarean section. Examination revealed extensive cellulitis with associated abdominal abscess. Staphylococcus aureus was identified in wound exudates and extensive surgical debridement undertaken day 11 postnatally due to continued febrile episodes and clinical deterioration, despite aggressive intravenous antibiotic therapy. Occlusive NPWT dressings were applied for a period of 3 weeks before discharge, as well as a further 5 weeks postdischarge into the community.NPWT was well tolerated and efficacious in infection clearance and wound healing during bacterial cellulitis. Wound healing averaged 1 cm per week before NPWT withdrawal; cessation of NPWT before full wound closure resulted in significantly reduced healing rate, increased purulent discharges, and skin irritation, highlighting the efficacy of NPWT. Five-month follow-up in the clinic found the wound to be fully healed with no additional scarring beyond the boundaries of the original Cesarean incision. The patient was pleased with treatment outcomes, reporting no lasting pain or discomfort from the scar.

CONCLUSIONS

This report represents the first documented use of NPWT to aid healing of an actively infected, open wound following extensive surgical debridement 10 days post-Cesarean section, confirming both the efficacy and tolerability of NPWT for the treatment of severe bacterial cellulitis in obstetric debridement.

摘要

引言

剖宫产术后细菌性蜂窝织炎较为罕见。负压伤口治疗(NPWT)在各种医学专科中广泛应用;然而其在产科的有效性仍是一个有争议的话题——主要用作高危患者群体二期愈合的辅助手段。其在剖宫产术后活动性感染伤口治疗中的应用记录并不充分。在此,我们记录了NPWT在治疗产后一例异常严重的伴有腹部脓肿的细菌性蜂窝织炎中的应用。我们提供了主要手术清创后伤口进展的独特照片时间线,记录了两种不同NPWT系统(RENASYS GO和PICO,施乐辉公司)的有效性。我们报告了使用这些NPWT系统时遇到的问题以及为提高疗效和患者体验而采取的“临时”解决方案。一名34岁的初产白种女性,既往无感染病史或危险因素,体重指数(BMI)正常,在急诊剖宫产术后7天出现严重腹痛、肿胀及广泛的腹部发红。检查发现广泛的蜂窝织炎伴有相关腹部脓肿。伤口渗出物中鉴定出金黄色葡萄球菌,尽管进行了积极的静脉抗生素治疗,但由于持续发热和临床病情恶化,在产后第11天进行了广泛的手术清创。出院前应用封闭性NPWT敷料3周,出院后在社区又应用了5周。NPWT耐受性良好,在细菌性蜂窝织炎的感染清除和伤口愈合方面有效。在停用NPWT前,伤口愈合平均每周1厘米;在伤口完全闭合前停止NPWT导致愈合速度显著降低、脓性分泌物增加及皮肤刺激,突出了NPWT的有效性。门诊5个月随访发现伤口完全愈合,除了原剖宫产切口边界外没有额外的瘢痕形成。患者对治疗结果满意,称瘢痕没有持续疼痛或不适。

结论

本报告是首次记录在剖宫产术后10天进行广泛手术清创后使用NPWT辅助治疗活动性感染开放性伤口,证实了NPWT在产科清创中治疗严重细菌性蜂窝织炎的有效性和耐受性。

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