鼻孤立性髓外浆细胞瘤十年后出现多发性原发性皮肤浆细胞瘤：一例疑难病例。

Multiple primary cutaneous plasmacytoma a decade after a nasal solitary extramedullary plasmacytoma: a puzzling case.

作者信息

González-Calle Verónica, Jorge-Finnigan Conrado, Santos-Durán Juan Carlos, López-Cadenas Felix, Ocio Enrique María, García-Sanz Ramón, Santos-Briz Ángel, Fernández-López Emilia, San Miguel Jesús, Mateos María-Victoria, Román-Curto Concha

机构信息

Department of Hematology Complejo Asistencial Universitario de Salamanca/Instituto de investigación biomédica de Salamanca (CAUSA/IBSAL) Salamanca Spain.

Department of Dermatology Complejo Asistencial Universitario de Salamanca/Instituto de investigación biomédica de Salamanca (CAUSA/IBSAL) Salamanca Spain; Present address: Department of Dermatology Hospital Santos Reyes Aranda de Duero Spain.

出版信息

Clin Case Rep. 2016 Oct 11;4(12):1096-1100. doi: 10.1002/ccr3.706. eCollection 2016 Dec.

DOI:10.1002/ccr3.706

PMID:27980740

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5134131/

Abstract

Primary cutaneous plasmacytoma should be in the differential diagnosis in case of solitary or multiple erythematous-violaceous nodules or papules. The diagnosis relies on clinical, histological, and immunochemical findings, without underlying evidence of multiple myeloma. Treatment should be individualized, and agents such as bortezomib or lenalidomide have shown to be effective.

摘要

对于孤立性或多发性红斑紫罗兰色结节或丘疹病例，原发性皮肤浆细胞瘤应列入鉴别诊断。诊断依赖于临床、组织学和免疫化学检查结果，且无多发性骨髓瘤的潜在证据。治疗应个体化，硼替佐米或来那度胺等药物已显示有效。